DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment conv and 18w

DIOPT Version :9

Sequence 1:NP_001286416.1 Gene:conv / 36588 FlyBaseID:FBgn0261269 Length:1092 Species:Drosophila melanogaster
Sequence 2:NP_476814.1 Gene:18w / 37277 FlyBaseID:FBgn0004364 Length:1385 Species:Drosophila melanogaster


Alignment Length:1068 Identity:253/1068 - (23%)
Similarity:430/1068 - (40%) Gaps:229/1068 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 LSHVGLLGFGI---LGKAKELVIDGHAFQQLPKDLFAGQEIANSLGIIRVT---------NGNLS 187
            |.|...|..|:   |.|..||.||....|::|.:.|.|     .:.:.|:|         .|...
  Fly    75 LLHASELAPGLFRQLQKLSELRIDACKLQRVPPNAFEG-----LMSLKRLTLESHNAVWGPGKTL 134

  Fly   188 DLPIETFQPLRKLKTLDLHGN----------------QLENLKRNQFKNLR-------------- 222
            :|..::||.|::|..|.|..|                ||.||.:|:.::..              
  Fly   135 ELHGQSFQGLKELSELHLGDNNIRQLPEGVWCSMPSLQLLNLTQNRIRSAEFLGFSEKLCAGSAL 199

  Fly   223 -----------ELEVLDISHNQIKKL-EAQHIADLTKLGWCNVSHNALSELSRGTFARNSVLKVL 275
                       ||:.||:|.|:::.| :|...:.|.:|...::.||.:|.|:....|..|.|:||
  Fly   200 SNANGAVSGGSELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVL 264

  Fly   276 HLSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRLKK--IEFQMF 338
            ::|:|.:..|.:.:|.|.:.||.|.|..|.|.::.:|....:.::..:||:.|:|..  ::...|
  Fly   265 NISYNHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGNQLTSHHVDNSTF 329

  Fly   339 TQMNYVELLDLAENNITKIEKNSFKDIY-QAIINVSHNALELIETAAFENCVNITVLDLSHNRLA 402
            ..:..:.:|:|:.|.:|:|...:||::| ..|:::.:|::..||..||....|:..|:|:.|||.
  Fly   330 AGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRLH 394

  Fly   403 NFSRRSFDETTFATYFQLSYNNLTNLAQI-PIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTI 466
            ....|.|:.....|...|: |||.::.:. ..:|.:.||.|:.|.|.:||:|: ....|..|.|:
  Fly   395 TLDNRIFNGLYVLTKLTLN-NNLVSIVESQAFRNCSDLKELDLSSNQLTEVPE-AVQDLSMLKTL 457

  Fly   467 DVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAK 531
            |:..|.||...|..|:.|..|..:.|..|.:..|....|..||.|..::|:.|.:.|:.||:..|
  Fly   458 DLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDK 522

  Fly   532 LTSLRQLYLNNN---QLEKLFQLPISLNELYFSHNRL-----TNIPSGTWPVMNSLIYLDLSHNQ 588
            .|.:..:.|:.|   .:..:|....||..|..|.|.|     ..|||       :|.:||:..|.
  Fly   523 NTEIEAIRLDKNFLTDINGIFATLASLLWLNLSENHLVWFDYAFIPS-------NLKWLDIHGNY 580

  Fly   589 LGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLF 653
            :....|.......:.|..|...:|.|::  ..|::|.::::.|.:.||.|..::.:.|.....|.
  Fly   581 IEALGNYYKLQEEIRVTTLDASHNRITE--IGAMSVPNSIELLFINNNIIGQIQANTFVDKTRLA 643

  Fly   654 ELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDNKT- 717
            .::||.|.:..||..|         |.::....:....:.::| .:....|.|...|.:::|.| 
  Fly   644 RVDLYANVLSKISLNA---------LRVAPVSAEKPVPEFYLG-GNPFECDCSMEWLQRINNLTT 698

  Fly   718 --NGVLDDLLSLETLDLSHNRIS------------FVTKKTFPSH--------QY---------- 750
              :..:.||.::|.| :.|:|.:            ||.|  :.||        :|          
  Fly   699 RQHPHVVDLGNIECL-MPHSRSAPLRPLASLSASDFVCK--YESHCPPTCHCCEYEQCECEVICP 760

  Fly   751 -----------------------------IPYNLRNLNLSYNLMPILTYDITFGTKKLVRLDVSH 786
                                         ||.::.:|.|..|.||.|......|.:.|..|.::.
  Fly   761 GNCSCFHDATWATNIVDCGRQDLAALPNRIPQDVSDLYLDGNNMPELEVGHLTGRRNLRALYLNA 825

  Fly   787 NQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQNLSWLDLSHNKIYHLPFANLVKVK 851
            :.:..|:.|.::...:|:.|.:..|:|:.|:..|  |.....|..|.|.:|.:.|:..|....:.
  Fly   826 SNLMTLQNGSLAQLVNLRVLHLENNKLTALEGTE--FRSLGLLRELYLHNNMLTHISNATFEPLV 888

  Fly   852 SLKYVDLTNNSLEDVPASIVGSMRNGSQVLLAG-NPLHCGC-NARPLKYFMLQQTIAGEDLKSIY 914
            ||:.:.|.||.|..:|..   ..|:..|.|..| |...|.| ..|.|..|:....:...|...||
  Fly   889 SLEVLRLDNNRLSSLPHL---QYRHSLQGLTLGRNAWSCRCQQLRELAQFVSDNAMVVRDAHDIY 950

  Fly   915 CGTPALIKDKQLISLDDEYLHCAEDEQEMYKGIDYEQLTDVRFREVKTNK-----------AGML 968
            |....:.::.:||.             .:..|.|...|.|.....:.:::           |.:|
  Fly   951 CLDAGIKRELELIG-------------NLANGPDCSDLLDASASNISSSQDLAGGYRLPLLAAVL 1002

  Fly   969 TLCWYV---------------------------SGFSDVSDFHVYIRSSSNDVLH-QSDYAYNNR 1005
            .|.:.|                           ..|.|....:..|      :|| :.||.:..|
  Fly  1003 VLIFLVVVLIIVFVFRESVRMWLFAHYGVRVCEPRFEDAGKLYDAI------ILHSEKDYEFVCR 1061

  Fly  1006 TAQIPVEELSTLGEEKLRGAEICIVSRD 1033
            .....:|.    |....|   :||..||
  Fly  1062 NIAAELEH----GRPPFR---LCIQQRD 1082

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
convNP_001286416.1 leucine-rich repeat 125..148 CDD:275380 5/15 (33%)
leucine-rich repeat 150..175 CDD:275380 8/24 (33%)
leucine-rich repeat 176..199 CDD:275380 7/31 (23%)
LRR_8 198..258 CDD:290566 21/101 (21%)
leucine-rich repeat 200..223 CDD:275380 9/63 (14%)
LRR_RI 201..545 CDD:238064 107/392 (27%)
leucine-rich repeat 224..271 CDD:275380 14/47 (30%)
LRR_8 245..306 CDD:290566 21/60 (35%)
leucine-rich repeat 272..295 CDD:275380 8/22 (36%)
LRR_8 296..354 CDD:290566 15/59 (25%)
leucine-rich repeat 296..319 CDD:275380 7/22 (32%)
LRR_8 322..401 CDD:290566 23/81 (28%)
leucine-rich repeat 322..343 CDD:275380 5/22 (23%)
leucine-rich repeat 344..367 CDD:275380 8/23 (35%)
leucine-rich repeat 371..390 CDD:275380 5/18 (28%)
leucine-rich repeat 391..414 CDD:275380 7/22 (32%)
leucine-rich repeat 416..438 CDD:275380 6/22 (27%)
LRR_8 437..495 CDD:290566 20/57 (35%)
leucine-rich repeat 439..462 CDD:275380 9/22 (41%)
leucine-rich repeat 463..486 CDD:275380 9/22 (41%)
LRR_RI 486..738 CDD:238064 63/262 (24%)
LRR_8 486..545 CDD:290566 17/61 (28%)
leucine-rich repeat 487..510 CDD:275380 6/22 (27%)
leucine-rich repeat 511..534 CDD:275380 7/22 (32%)
leucine-rich repeat 535..554 CDD:275380 3/21 (14%)
LRR_8 554..614 CDD:290566 17/64 (27%)
leucine-rich repeat 555..578 CDD:275380 8/27 (30%)
leucine-rich repeat 579..603 CDD:275380 5/23 (22%)
leucine-rich repeat 604..627 CDD:275380 6/22 (27%)
LRR_8 626..710 CDD:290566 16/83 (19%)
leucine-rich repeat 628..649 CDD:275380 5/20 (25%)
leucine-rich repeat 652..672 CDD:275380 7/19 (37%)
LRR_8 698..765 CDD:290566 22/128 (17%)
leucine-rich repeat 700..726 CDD:275380 7/28 (25%)
leucine-rich repeat 727..745 CDD:275380 7/29 (24%)
LRR_8 777..839 CDD:290566 15/61 (25%)
leucine-rich repeat 779..802 CDD:275380 4/22 (18%)
leucine-rich repeat 829..852 CDD:275380 6/22 (27%)
18wNP_476814.1 leucine-rich repeat 66..91 CDD:275380 5/15 (33%)
leucine-rich repeat 92..115 CDD:275380 8/27 (30%)
LRR_8 115..181 CDD:290566 16/65 (25%)
leucine-rich repeat 116..146 CDD:275380 7/29 (24%)
leucine-rich repeat 147..170 CDD:275380 4/22 (18%)
leucine-rich repeat 171..201 CDD:275380 5/29 (17%)
LRR_RI 210..464 CDD:238064 77/255 (30%)
leucine-rich repeat 212..236 CDD:275380 8/23 (35%)
LRR_8 235..295 CDD:290566 20/59 (34%)
leucine-rich repeat 237..260 CDD:275380 6/22 (27%)
leucine-rich repeat 261..284 CDD:275380 8/22 (36%)
LRR_8 283..345 CDD:290566 15/61 (25%)
leucine-rich repeat 285..308 CDD:275380 7/22 (32%)
leucine-rich repeat 309..334 CDD:275380 5/24 (21%)
LRR_8 334..393 CDD:290566 18/58 (31%)
leucine-rich repeat 335..358 CDD:275380 7/22 (32%)
leucine-rich repeat 359..382 CDD:275380 6/22 (27%)
LRR_8 382..441 CDD:290566 19/59 (32%)
leucine-rich repeat 383..406 CDD:275380 7/22 (32%)
leucine-rich repeat 407..430 CDD:275380 6/23 (26%)
LRR_8 431..488 CDD:290566 21/57 (37%)
leucine-rich repeat 431..451 CDD:275380 8/20 (40%)
leucine-rich repeat 454..477 CDD:275380 9/22 (41%)
LRR_8 477..559 CDD:290566 23/81 (28%)
leucine-rich repeat 478..499 CDD:275380 5/20 (25%)
leucine-rich repeat 502..525 CDD:275380 7/22 (32%)
leucine-rich repeat 526..548 CDD:275380 3/21 (14%)
leucine-rich repeat 590..617 CDD:275380 6/28 (21%)
leucine-rich repeat 618..641 CDD:275380 5/22 (23%)
leucine-rich repeat 642..689 CDD:275380 11/56 (20%)
LRRCT 679..736 CDD:214507 13/57 (23%)
leucine-rich repeat 775..796 CDD:275380 2/20 (10%)
LRR_8 797..852 CDD:290566 14/54 (26%)
leucine-rich repeat 797..817 CDD:275380 7/19 (37%)
leucine-rich repeat 818..841 CDD:275380 4/22 (18%)
LRR_8 841..900 CDD:290566 18/60 (30%)
leucine-rich repeat 842..865 CDD:275380 7/24 (29%)
LRR_4 866..907 CDD:289563 13/43 (30%)
leucine-rich repeat 866..889 CDD:275380 6/22 (27%)
leucine-rich repeat 890..911 CDD:275380 7/23 (30%)
TIR 1045..1183 CDD:214587 13/51 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.