DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conv and CG5096

DIOPT Version :9

Sequence 1:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	104/431 - (24%)
Similarity:	173/431 - (40%)	Gaps:	95/431 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   566 TNIPSGTWPVMNSLI------YLDLS----HNQLGDTLNGESF----TGLLVVQRLKLQNNGISQ 616
            |..|.....|::|.:      |:|.:    ..:|.|.|:.|.:    .|.:|.:.:.|::|.::.
  Fly    32 TETPKEKIKVIDSKLCKKCNCYIDTNLLDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTS 96

  Fly   617 PPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQ------VKDISK-----RAF 670
            .|   :.....::.|:|.||.|.::...||..|..|..|:|..|:      |.|:.|     :.|
  Fly    97 VP---ILPKYDVENLYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDF 158

  Fly   671 EGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDLSHN 735
            |.|..|.||||..|.:.:|..|:|..:|.:..|.|..||...:|..:...:..|.||:.||:|:.
  Fly   159 ESLENLKTLNLGYNDLHSLDADLFEHIPHIEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYM 223

  Fly   736 RIS---------------FVTK----KTFPSHQYIPYNLRNLNLSYNLMPILTYDITF-GTKKLV 780
            .|.               |:..    ...|.......||.:|.|:.|.:..|..|..| ...||.
  Fly   224 EIDDLPDTILHGPRDLEIFIAAGNLFNQLPKALKYATNLTSLVLNENPIENLIGDNVFPPLTKLT 288

  Fly   781 RLDVSH-NQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQNLS---WLD-------- 833
            .|.::. :::..:..|..|...||..|.:|.|:|.|...||   .|.:|::   :||
  Fly   289 HLSMTFMSKLYKIGPGAFSELQSLTELILSDNKLLNEIDEE---ALSKNVTGGQYLDYPPLEKVY 350

  Fly   834 LSHNKIYHLPFANLVKVKSLKYVDLTNN-----SLEDVPASIVGSMRNGSQVLLAGNPLHCGCNA 893
            |::..:..||...||:...||.:||..|     ...|...:::....|.:..:||
  Fly   351 LNNCNVSTLPKELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKTTPVLA---------- 405

  Fly   894 RPLKYFMLQQTIAGEDLKSIYCGTPALIKDKQLISLDDEYL 934
                             |.:.||.|..:.|..|:.:.:|::
  Fly   406 -----------------KDVKCGGPNKLNDVTLLRVANEHM 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_001286416.1	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		LRR_8	198..258	CDD:290566
		leucine-rich repeat	200..223	CDD:275380
		LRR_RI	201..545	CDD:238064
		leucine-rich repeat	224..271	CDD:275380
		LRR_8	245..306	CDD:290566
		leucine-rich repeat	272..295	CDD:275380
		LRR_8	296..354	CDD:290566
		leucine-rich repeat	296..319	CDD:275380
		LRR_8	322..401	CDD:290566
		leucine-rich repeat	322..343	CDD:275380
		leucine-rich repeat	344..367	CDD:275380
		leucine-rich repeat	371..390	CDD:275380
		leucine-rich repeat	391..414	CDD:275380
		leucine-rich repeat	416..438	CDD:275380
		LRR_8	437..495	CDD:290566
		leucine-rich repeat	439..462	CDD:275380
		leucine-rich repeat	463..486	CDD:275380
		LRR_RI	486..738	CDD:238064	54/196 (28%)
		LRR_8	486..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		leucine-rich repeat	535..554	CDD:275380
		LRR_8	554..614	CDD:290566	14/61 (23%)
		leucine-rich repeat	555..578	CDD:275380	3/11 (27%)
		leucine-rich repeat	579..603	CDD:275380	7/37 (19%)
		leucine-rich repeat	604..627	CDD:275380	3/22 (14%)
		LRR_8	626..710	CDD:290566	31/94 (33%)
		leucine-rich repeat	628..649	CDD:275380	7/20 (35%)
		leucine-rich repeat	652..672	CDD:275380	8/30 (27%)
		LRR_8	698..765	CDD:290566	20/85 (24%)
		leucine-rich repeat	700..726	CDD:275380	6/25 (24%)
		leucine-rich repeat	727..745	CDD:275380	6/36 (17%)
		LRR_8	777..839	CDD:290566	19/73 (26%)
		leucine-rich repeat	779..802	CDD:275380	4/23 (17%)
		leucine-rich repeat	829..852	CDD:275380	7/33 (21%)
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	84/314 (27%)
		leucine-rich repeat	85..104	CDD:275380	3/21 (14%)
		LRR_8	105..174	CDD:290566	24/68 (35%)
		leucine-rich repeat	105..128	CDD:275380	8/22 (36%)
		leucine-rich repeat	129..163	CDD:275380	10/33 (30%)
		LRR_8	163..222	CDD:290566	20/58 (34%)
		leucine-rich repeat	164..187	CDD:275380	9/22 (41%)
		leucine-rich repeat	188..214	CDD:275380	6/25 (24%)
		leucine-rich repeat	215..238	CDD:275380	5/22 (23%)
		leucine-rich repeat	239..261	CDD:275380	2/21 (10%)
		LRR_8	260..322	CDD:290566	18/61 (30%)
		leucine-rich repeat	262..286	CDD:275380	7/23 (30%)
		leucine-rich repeat	287..311	CDD:275380	4/23 (17%)
		leucine-rich repeat	346..369	CDD:275380	5/22 (23%)
		leucine-rich repeat	370..388	CDD:275380	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010