Protein Alignment conv and Lrig3

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_796126.4
• Gene: Lrig3 / 320398
• MGIID: 2443955
• Length: 1117
• Species: Mus musculus
• Alignment Length: 440
• Identity: 123/440 - (27%)
• Similarity: 202/440 - (45%)
• Gaps: 76/440 - (17%)

  Fly   275 LHLSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSI-ARIGTIDLARNRLKKIEFQMF 338
            |.||||:::.:..:|...::.|:.:.|::|.|..|  ...||| |.|..:.||.|.:.||..:..
Mouse    79 LDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETI--PNLGSISANIRQLSLAGNAIDKILPEQL 141

  Fly   339 TQMNYVELLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCVNITVLDLSHNRLAN 403
            .....:|.|||:.|||::: :.:|..:....:.:::|.:..:|...|:|..: |:|.|..||
Mouse   142 EAFQSLETLDLSNNNISEL-RTAFPPLQLKYLYINNNRVSSMEPGYFDNLAS-TLLVLKLNR--- 201

  Fly   404 FSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDV 468
                                                       |.|:.||...| ||.:|..:::
Mouse   202 -------------------------------------------NRISAIPPKMF-KLPQLQHLEL 222

  Fly   469 SHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLT 533
            :.|.|.::....||.|.:|:|:.:..|.:.::....|..|..:..:.|.||.|..:.:|.|..|.
Mouse   223 NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLL 287

  Fly   534 SLRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGESF 598
            .||:|:|                    |.|.:..|....|.....|..|||:.|.| ..|:..||
Mouse   288 MLRELHL--------------------SQNAINRISPDAWEFCQKLSELDLTFNHL-SRLDDSSF 331

  Fly   599 TGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNIT-TLE--RSAFGKLPVLFELNLYGN 660
            .||.::..|.:.||.:|.....|...:::|:.|.|.||.|: |:|  ..||..|..|.:|.|.||
Mouse   332 LGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSGAFSGLDRLRQLILQGN 396

  Fly   661 QVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSL 710
            :::.|:|:||.||..|..|:||.|.|.:||::.|..:..|:.|.|:.:||
Mouse   397 RIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		PPP1R42	191..359	CDD:455733	28/84 (33%)
		LRR_8	198..258	CDD:404697
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	224..271	CDD:275380
		leucine-rich repeat	272..295	CDD:275380	6/19 (32%)
		leucine-rich repeat	296..319	CDD:275380	8/23 (35%)
		leucine-rich repeat	322..343	CDD:275380	5/20 (25%)
		leucine-rich repeat	344..367	CDD:275380	8/22 (36%)
		LRR	346..718	CDD:443914	101/368 (27%)
		leucine-rich repeat	371..390	CDD:275380	4/18 (22%)
		leucine-rich repeat	391..414	CDD:275380	5/22 (23%)
		leucine-rich repeat	416..438	CDD:275380	0/21 (0%)
		leucine-rich repeat	439..462	CDD:275380	7/22 (32%)
		leucine-rich repeat	463..486	CDD:275380	6/22 (27%)
		leucine-rich repeat	487..510	CDD:275380	5/22 (23%)
		leucine-rich repeat	511..534	CDD:275380	7/22 (32%)
		leucine-rich repeat	535..554	CDD:275380	4/18 (22%)
		leucine-rich repeat	555..578	CDD:275380	4/22 (18%)
		leucine-rich repeat	579..603	CDD:275380	11/23 (48%)
		leucine-rich repeat	604..627	CDD:275380	5/22 (23%)
		leucine-rich repeat	628..649	CDD:275380	10/23 (43%)
		PPP1R42	631..849	CDD:455733	35/83 (42%)
		leucine-rich repeat	652..672	CDD:275380	9/19 (47%)
		leucine-rich repeat	700..726	CDD:275380	5/11 (45%)
		leucine-rich repeat	727..745	CDD:275380
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
Lrig3	NP_796126.4	LRRNT	46..74	CDD:214470
		LRR 1	75..98		6/18 (33%)
		leucine-rich repeat	76..99	CDD:275378	6/19 (32%)
		LRR	77..421	CDD:443914	113/413 (27%)
		LRR 2	99..120		7/22 (32%)
		leucine-rich repeat	100..146	CDD:275378	15/47 (32%)
		LRR 3	122..143		6/20 (30%)
		LRR 4	146..168		8/22 (36%)
		leucine-rich repeat	147..168	CDD:275380	8/21 (38%)
		leucine-rich repeat	169..192	CDD:275380	4/22 (18%)
		LRR 5	169..189		3/19 (16%)
		LRR 6	193..214		10/67 (15%)
		leucine-rich repeat	194..216	CDD:275380	11/68 (16%)
		LRR 7	216..237		4/20 (20%)
		leucine-rich repeat	217..240	CDD:275380	6/22 (27%)
		LRR 8	240..261		4/20 (20%)
		leucine-rich repeat	241..264	CDD:275380	5/22 (23%)
		LRR 9	264..285		6/20 (30%)
		leucine-rich repeat	265..288	CDD:275380	7/22 (32%)
		LRR 10	288..309		8/40 (20%)
		leucine-rich repeat	289..312	CDD:275380	8/42 (19%)
		LRR 11	312..333		9/21 (43%)
		leucine-rich repeat	313..336	CDD:275380	11/23 (48%)
		LRR 12	336..357		5/20 (25%)
		leucine-rich repeat	337..360	CDD:275380	5/22 (23%)
		LRR 13	360..382		8/21 (38%)
		leucine-rich repeat	361..385	CDD:275380	10/23 (43%)
		LRR 14	387..408		9/20 (45%)
		leucine-rich repeat	388..411	CDD:275380	11/22 (50%)
		LRR 15	411..432		9/20 (45%)
		leucine-rich repeat	412..433	CDD:275380	9/20 (45%)
		PCC	416..>494	CDD:188093	12/31 (39%)
		Ig_3	498..585	CDD:464046
		IgI_LRIG1-like	604..694	CDD:409420
		Ig strand A	604..607	CDD:409420
		Ig strand A'	611..615	CDD:409420
		Ig strand B	618..627	CDD:409420
		Ig strand C	633..638	CDD:409420
		Ig strand C'	641..643	CDD:409420
		Ig strand D	651..655	CDD:409420
		Ig strand E	659..666	CDD:409420
		Ig strand F	672..680	CDD:409420
		Ig strand G	683..694	CDD:409420
		I-set	697..784	CDD:400151
		Ig strand B	714..718	CDD:409544
		Ig strand C	727..731	CDD:409544
		Ig strand E	750..754	CDD:409544
		Ig strand F	764..769	CDD:409544
		Ig strand G	777..780	CDD:409544
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1019..1093