Protein Alignment conv and Tsku

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_001009965.2
• Gene: Tsku / 308843
• RGDID: 1359311
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 93/322 - (28%)
• Similarity: 134/322 - (41%)
• Gaps: 84/322 - (26%)

  Fly   394 LDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFP 458
            ||||.|||         ||             .|.:.:.....|.|..|:.|:|.:|.|....|.
  Rat    64 LDLSSNRL---------ET-------------VNESVLGGPGYTTLAGLDLSHNLLTSITPTAFS 106

  Fly   459 KLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGT--LPTLLEMDLSHNEL 521
            :|..|.::|:|||.::::...|| |...|..|:||||.:||:..|.|.|  ....|.:|||||.:
  Rat   107 RLRYLESLDLSHNGLAALPAEVF-TSSPLSDINLSHNRLREVSISAFTTHSQGRALHVDLSHNLI 170

  Fly   522 VSVV----RGSLAKLTSLRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPS-GTWPVMNSLIY 581
            ..::    |.||:..|                     :..|..|.|||..:|: ...|    |.|
  Rat   171 HRLLPYPARASLSAPT---------------------IQSLNLSWNRLRAVPNLRDLP----LRY 210

  Fly   582 LDLSHNQLGDTLNGESFTGLLVVQRLKLQN-NGISQ-PPKDAVAVMSTLQYLHLENNNITTLERS 644
            |.|..|.|. |:|..:|.||..:..|.|.: .||.| ||                         .
  Rat   211 LSLDGNPLA-TINPGAFMGLAGLTHLSLASLQGILQLPP-------------------------H 249

  Fly   645 AFGKLPVLFELNLYGN-QVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDL 705
            .|.:||.|..|:|.|| ::|......|.||..|..|:||.:.:..|...:...||:|:::.:
  Rat   250 GFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPETLLHHLPALQSVSV 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		PPP1R42	191..359	CDD:455733
		LRR_8	198..258	CDD:404697
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	224..271	CDD:275380
		leucine-rich repeat	272..295	CDD:275380
		leucine-rich repeat	296..319	CDD:275380
		leucine-rich repeat	322..343	CDD:275380
		leucine-rich repeat	344..367	CDD:275380
		LRR	346..718	CDD:443914	93/322 (29%)
		leucine-rich repeat	371..390	CDD:275380
		leucine-rich repeat	391..414	CDD:275380	9/19 (47%)
		leucine-rich repeat	416..438	CDD:275380	1/21 (5%)
		leucine-rich repeat	439..462	CDD:275380	8/22 (36%)
		leucine-rich repeat	463..486	CDD:275380	8/22 (36%)
		leucine-rich repeat	487..510	CDD:275380	11/24 (46%)
		leucine-rich repeat	511..534	CDD:275380	9/26 (35%)
		leucine-rich repeat	535..554	CDD:275380	0/18 (0%)
		leucine-rich repeat	555..578	CDD:275380	7/23 (30%)
		leucine-rich repeat	579..603	CDD:275380	11/23 (48%)
		leucine-rich repeat	604..627	CDD:275380	7/24 (29%)
		leucine-rich repeat	628..649	CDD:275380	1/20 (5%)
		PPP1R42	631..849	CDD:455733	20/76 (26%)
		leucine-rich repeat	652..672	CDD:275380	7/20 (35%)
		leucine-rich repeat	700..726	CDD:275380	1/6 (17%)
		leucine-rich repeat	727..745	CDD:275380
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
Tsku	NP_001009965.2	LRR 1	60..80		10/37 (27%)
		leucine-rich repeat	63..86	CDD:275380	10/43 (23%)
		LRR	<85..>306	CDD:443914	82/272 (30%)
		LRR 2	86..107		7/20 (35%)
		leucine-rich repeat	90..110	CDD:275380	7/19 (37%)
		LRR 3	110..131		7/21 (33%)
		leucine-rich repeat	111..133	CDD:275380	8/22 (36%)
		LRR 4	133..154		10/20 (50%)
		leucine-rich repeat	134..159	CDD:275380	11/24 (46%)
		leucine-rich repeat	160..186	CDD:275380	9/25 (36%)
		LRR 5	160..180		6/19 (32%)
		LRR 6	186..207		7/41 (17%)
		leucine-rich repeat	187..205	CDD:275380	6/17 (35%)
		leucine-rich repeat	208..231	CDD:275380	11/23 (48%)
		LRR 7	208..228		9/20 (45%)
		LRR 8	231..253		8/46 (17%)
		leucine-rich repeat	232..256	CDD:275380	9/48 (19%)
		LRR 9	256..277		6/20 (30%)
		leucine-rich repeat	257..281	CDD:275380	9/23 (39%)
		LRR 10	281..302		5/20 (25%)
		leucine-rich repeat	282..305	CDD:275380	6/22 (27%)