Protein Alignment conv and nrros

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_001231915.1
• Gene: nrros / 100498580
• XenbaseID: XB-GENE-986206
• Length: 679
• Species: Xenopus tropicalis
• Alignment Length: 757
• Identity: 170/757 - (22%)
• Similarity: 276/757 - (36%)
• Gaps: 276/757 - (36%)

  Fly   160 QQLPKDLFAGQEIANSLGIIRVTNGNLSDLPIETFQPLRKLKTLDLHGNQLENLKRNQFKNLREL 224
            |.||.|:   ||:......||..:.|       :|.....|..|.|..|::|.::...|..:|.|
 Frog    53 QNLPTDI---QELLLDFNQIRFLHKN-------SFLRYHDLTNLSLRSNRMEFVEPGAFNGIRSL 107

  Fly   225 EVLDISHNQI-----------------KKLEAQHIADLTKLGWCNVSHNALSELSRGTFARNSVL 272
            :||.:.:|.|                 |:|:...  ::..:...:|.|..|:.|.|
 Frog   108 KVLSLQNNTISMEYELTSAALRLTPSLKELDLSR--NMLTMDMVSVLHQNLTSLER--------- 161

  Fly   273 KVLHLSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRLKKIEFQM 337
              |.|.:|.|.|||...|.|:..|:.|.|..|.:.:|..|||..:.::..:|||.|.|..|
 Frog   162 --LFLDNNIIMRLDQTVFEGLVHLKELSLQWNYIYEIEDGTFEGLVKLKKLDLAYNLLPCI---- 220

  Fly   338 FTQMNYVELLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCVNITVLDLSHNRLA 402
                        .:..:|:|:          ::|:|.|.||..::...:...::.:||:|:|:|.
 Frog   221 ------------GDFRLTQIQ----------MLNLSFNNLEWFQSQETDVEFHLEILDISNNQLL 263

  Fly   403 NFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTID 467
            .|                           |:                       .|:.:.|||:.
 Frog   264 FF---------------------------PL-----------------------LPRQHRLHTLL 278

  Fly   468 VSHNNISSIFNGVFQTLFSLRSIDLSHNSMREI------KSSTFGTLPTLLEMDLSHNELVSVVR 526
            :| ||....:..:|.|..|.....:..|::..:      .......|.||..:|:|||:......
 Frog   279 LS-NNRMRFYGDIFGTNTSRADFLIVENNITSVTTVDLWSDDIHSNLSTLHYLDMSHNQFAFFPH 342

  Fly   527 GSLAKLTSLRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLGD 591
            |..:.::||..|.||.|.|:.....|.::..|                    |..||||:|:|
 Frog   343 GFFSNMSSLAYLKLNWNCLQVFSVSPSNITSL--------------------LDELDLSNNEL-- 385

  Fly   592 TLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELN 656
                           |:||.:.||.      .::| |.|.:|.:|                   |
 Frog   386 ---------------LELQADNISP------GILS-LSYFNLSSN-------------------N 409

  Fly   657 LYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTL-QNDIFVG---------LPSLRNLDLS----- 706
            ||     ::.|..|..:.::.|:::|:|.:... |:::.:|         :||||.|.||
 Frog   410 LY-----NLPKNIFTSMTRIHTIDMSNNPLHLCSQSELRMGEGKCVDVRNVPSLRRLYLSGCGME 469

  Fly   707 --------FNSLTKLDNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPYNLRNLNLSYN 763
                    .|:||.                 ||||:|.|..:|        ::....|.|. |..
 Frog   470 LGLQRVFYGNTLTH-----------------LDLSYNNIKGIT--------FLADTARTLQ-SLF 508

  Fly   764 LMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQN 828
            |...|.::||..                     .|.|.||..||:|.|.|:.         .|.:
 Frog   509 LRSCLAFNITVD---------------------FSVFMSLTVLDISGNALTT---------FPAS 543

  Fly   829 LS-----WLDLSHNKIYHLPFANLVK-VKSLKYVDLTNNSLE 864
            |:     :|||.:|.:..||..|..: :.|||.|.::|||.:
 Frog   544 LTGLALHYLDLHNNNLISLPLYNTQRLIGSLKIVYISNNSFD 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380	6/14 (43%)
		leucine-rich repeat	176..199	CDD:275380	4/22 (18%)
		PPP1R42	191..359	CDD:455733	45/184 (24%)
		LRR_8	198..258	CDD:404697	16/76 (21%)
		leucine-rich repeat	200..223	CDD:275380	6/22 (27%)
		leucine-rich repeat	224..271	CDD:275380	12/63 (19%)
		leucine-rich repeat	272..295	CDD:275380	9/22 (41%)
		leucine-rich repeat	296..319	CDD:275380	8/22 (36%)
		leucine-rich repeat	322..343	CDD:275380	6/20 (30%)
		leucine-rich repeat	344..367	CDD:275380	2/22 (9%)
		LRR	346..718	CDD:443914	79/400 (20%)
		leucine-rich repeat	371..390	CDD:275380	5/18 (28%)
		leucine-rich repeat	391..414	CDD:275380	6/22 (27%)
		leucine-rich repeat	416..438	CDD:275380	1/21 (5%)
		leucine-rich repeat	439..462	CDD:275380	1/22 (5%)
		leucine-rich repeat	463..486	CDD:275380	8/22 (36%)
		leucine-rich repeat	487..510	CDD:275380	2/28 (7%)
		leucine-rich repeat	511..534	CDD:275380	6/22 (27%)
		leucine-rich repeat	535..554	CDD:275380	7/18 (39%)
		leucine-rich repeat	555..578	CDD:275380	1/22 (5%)
		leucine-rich repeat	579..603	CDD:275380	7/23 (30%)
		leucine-rich repeat	604..627	CDD:275380	5/22 (23%)
		leucine-rich repeat	628..649	CDD:275380	4/20 (20%)
		PPP1R42	631..849	CDD:455733	54/245 (22%)
		leucine-rich repeat	652..672	CDD:275380	5/19 (26%)
		leucine-rich repeat	700..726	CDD:275380	8/38 (21%)
		leucine-rich repeat	727..745	CDD:275380	7/17 (41%)
		leucine-rich repeat	779..802	CDD:275380	2/22 (9%)
		leucine-rich repeat	829..852	CDD:275380	8/28 (29%)
nrros	NP_001231915.1	LRR	7..342	CDD:443914	84/388 (22%)
		leucine-rich repeat	39..58	CDD:275380	3/4 (75%)
		leucine-rich repeat	59..82	CDD:275380	6/32 (19%)
		leucine-rich repeat	83..106	CDD:275380	6/22 (27%)
		leucine-rich repeat	107..133	CDD:275380	5/25 (20%)
		leucine-rich repeat	134..158	CDD:275380	5/25 (20%)
		leucine-rich repeat	159..182	CDD:275380	11/33 (33%)
		leucine-rich repeat	183..206	CDD:275380	8/22 (36%)
		leucine-rich repeat	207..227	CDD:275380	6/35 (17%)
		leucine-rich repeat	228..251	CDD:275380	6/32 (19%)
		LRR	231..>585	CDD:443914	116/528 (22%)
		leucine-rich repeat	274..326	CDD:275380	11/52 (21%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..399	CDD:275380	12/46 (26%)
		leucine-rich repeat	400..421	CDD:275380	9/44 (20%)
		leucine-rich repeat	424..457	CDD:275380	5/32 (16%)
		leucine-rich repeat	458..480	CDD:275380	5/21 (24%)
		leucine-rich repeat	481..503	CDD:275380	9/46 (20%)
		leucine-rich repeat	504..526	CDD:275380	8/43 (19%)
		leucine-rich repeat	527..548	CDD:275380	8/29 (28%)
		leucine-rich repeat	574..586	CDD:275378	6/12 (50%)