Protein Alignment conv and tlrs5

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: XP_002937550.2
• Gene: tlrs5 / 100489423
• XenbaseID: XB-GENE-22201327
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 178/632 - (28%)
• Similarity: 277/632 - (43%)
• Gaps: 150/632 - (23%)

  Fly   158 AFQQLPK-------DLFAGQEIANSLGIIRVTNGNLSDLPIETFQPLRKLKTLDLHGNQLENLKR 215
            :|.::|.       ||...|.:.  || .:||.|..| :....|:....|.||||.||::.||..
 Frog    63 SFNRIPSISQDSFPDLLHLQTLL--LG-SQVTPGTFS-VGKSAFRGFPNLITLDLGGNRIINLHP 123

  Fly   216 NQFKNLRELEVLDISHNQIKK--LEAQHIADLTKLGWCNVSHNALSELSRG-TFARNSVLKVLHL 277
            ..|:.|..||||.:.||.:.:  ||:....|||.|...::|.|.:..:... ||.:.|.:..|.|
 Frog   124 EAFEGLSWLEVLLLDHNGLDESVLESGMFKDLTSLKKLDLSFNNIRRVRPDPTFLKLSSISFLLL 188

  Fly   278 SHNQIARL---DANSFRGMRFLRRLFLSDNVL----TDIGRGTFGSIARIGTID---------LA 326
            ..|:::.|   |..:.:|.| |:.|.:|.|.|    |......|.:|. :||:|         :.
 Frog   189 KFNKVSMLCGEDLQNLQGRR-LQLLDMSSNPLQLSSTPHCTNPFNNIT-LGTLDVSSMGWNAEMV 251

  Fly   327 RNRLKKIEFQMFTQMNYVELLDLAE-------NNITKIEKNSFKDIYQAIINVSHNALELIETAA 384
            .|.::.|.   .||::|:::...|.       :|:....|::|..:
 Frog   252 ENFVRTIS---GTQVDYIKMRHTAGLGSGFGFHNLKDPNKDTFSGL------------------- 294

  Fly   385 FENCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSI 449
              |..|:.:||||:..:::...:.|
 Frog   295 --NSSNVQILDLSNGFISHLVPQLF---------------------------------------- 317

  Fly   450 TEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTL--PTLL 512
                 :.||||..|   |:|.|.|:.:.:|.|..|..|.|::||.|.:.|:..|:|..|  .:|.
 Frog   318 -----SAFPKLLSL---DLSSNQINRMSSGAFSGLGELVSLNLSGNLLGELMGSSFQGLGATSLK 374

  Fly   513 EMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKLFQLPISLNELYF---SHNRLTNI------ 568
            .:|||.|.:.:|..|:|...|:|..|.|.:|.|.|:  .|..|..:.|   ..||:::|
 Frog   375 TLDLSSNHIGAVQYGALDSFTALTSLNLRDNALNKI--PPTKLQGVTFVLLKQNRISDIYNIISF 437

  Fly   569 -PSGTWPVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLK---LQNNGI---SQPPKDAVAVMS 626
             |..|        .||||.|:|.|.   .|...:|.:|.||   |.:|.:   |.|....:...|
 Frog   438 CPHAT--------ILDLSSNRLTDF---RSLWQILELQSLKYLSLASNSLYRCSLPHTSNITRTS 491

  Fly   627 TLQYLHLENNNITTLERSA-----FGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGI 686
            .|.||.|.:|.:..:.:|.     |..|..|..|||..||:.:|....|..|..|.||:||.||.
 Frog   492 GLVYLDLSDNALGPVLKSGECGDIFMHLGSLKSLNLARNQLSNIPDTMFRSLSSLQTLDLSGNGF 556

  Fly   687 QTLQNDIFVGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDLS 733
            :.:|:::|.||.:|:.|:|..::|..|   ::.|||.|.|||::|||
 Frog   557 KEIQSNLFTGLTALKTLNLGKSNLVTL---SSSVLDPLGSLESIDLS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380	5/23 (22%)
		leucine-rich repeat	176..199	CDD:275380	7/22 (32%)
		PPP1R42	191..359	CDD:455733	54/193 (28%)
		LRR_8	198..258	CDD:404697	25/61 (41%)
		leucine-rich repeat	200..223	CDD:275380	11/22 (50%)
		leucine-rich repeat	224..271	CDD:275380	16/49 (33%)
		leucine-rich repeat	272..295	CDD:275380	6/25 (24%)
		leucine-rich repeat	296..319	CDD:275380	8/26 (31%)
		leucine-rich repeat	322..343	CDD:275380	6/29 (21%)
		leucine-rich repeat	344..367	CDD:275380	4/29 (14%)
		LRR	346..718	CDD:443914	105/401 (26%)
		leucine-rich repeat	371..390	CDD:275380	1/18 (6%)
		leucine-rich repeat	391..414	CDD:275380	5/22 (23%)
		leucine-rich repeat	416..438	CDD:275380	0/21 (0%)
		leucine-rich repeat	439..462	CDD:275380	4/22 (18%)
		leucine-rich repeat	463..486	CDD:275380	8/22 (36%)
		leucine-rich repeat	487..510	CDD:275380	9/24 (38%)
		leucine-rich repeat	511..534	CDD:275380	8/22 (36%)
		leucine-rich repeat	535..554	CDD:275380	7/18 (39%)
		leucine-rich repeat	555..578	CDD:275380	7/32 (22%)
		leucine-rich repeat	579..603	CDD:275380	8/23 (35%)
		leucine-rich repeat	604..627	CDD:275380	7/28 (25%)
		leucine-rich repeat	628..649	CDD:275380	7/25 (28%)
		PPP1R42	631..849	CDD:455733	41/108 (38%)
		leucine-rich repeat	652..672	CDD:275380	8/19 (42%)
		leucine-rich repeat	700..726	CDD:275380	9/25 (36%)
		leucine-rich repeat	727..745	CDD:275380	5/7 (71%)
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
tlrs5	XP_002937550.2	RNA1	<100..269	CDD:444072	52/173 (30%)
		LRR_8	106..168	CDD:404697	25/61 (41%)
		leucine-rich repeat	108..131	CDD:275380	11/22 (50%)
		leucine-rich repeat	132..157	CDD:275380	10/24 (42%)
		leucine-rich repeat	158..182	CDD:275380	5/23 (22%)
		leucine-rich repeat	183..208	CDD:275380	6/24 (25%)
		leucine-rich repeat	209..232	CDD:275380	6/22 (27%)
		LRR	291..632	CDD:443914	112/395 (28%)
		leucine-rich repeat	299..322	CDD:275380	6/67 (9%)
		leucine-rich repeat	323..346	CDD:275380	9/25 (36%)
		leucine-rich repeat	347..372	CDD:275380	9/24 (38%)
		leucine-rich repeat	373..396	CDD:275380	8/22 (36%)
		leucine-rich repeat	397..440	CDD:275380	12/44 (27%)
		leucine-rich repeat	418..431	CDD:275378	3/12 (25%)
		leucine-rich repeat	441..492	CDD:275380	17/61 (28%)
		leucine-rich repeat	493..521	CDD:275380	8/27 (30%)
		leucine-rich repeat	522..545	CDD:275380	9/22 (41%)
		leucine-rich repeat	546..569	CDD:275380	11/22 (50%)
		leucine-rich repeat	570..591	CDD:275380	8/23 (35%)