Protein Alignment beta4GalNAcTA and B4GALT2

DIOPT Version :10

• Sequence 1: NP_610946.1
• Gene: beta4GalNAcTA / 36585
• FlyBaseID: FBgn0027538
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_085076.2
• Gene: B4GALT2 / 8704
• HGNCID: 925
• Length: 401
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 140/400 - (35%)
• Similarity: 204/400 - (51%)
• Gaps: 66/400 - (16%)

  Fly    11 RFLAG-------AICLLLVLNF-----VGFRSDGGSATSLSKLSIRRVHKYAHIYGNASSDGAGG 63
            |.|.|       |:.||.:|:|     :.|..........|:.|.|..   ||....|:|..:..
Human    32 RLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGP---AHALHPAASSSSSS 93

  Fly    64 SEASRLPASPLALSKDRERDQELNGGPNSTIRTVIATANFTSIPQDLTRFLLGTKKFLPPRQKS- 127
            |..||                     ||       |||:.:.:|:..:.....|...|||...|
Human    94 SNCSR---------------------PN-------ATASSSGLPEVPSALPGPTAPTLPPCPDSP 130

  Fly   128 ---TSALLANCTDPDPRDGGPITPNTTLESLDVIEAELGPLLRPGGAFEPENCNAQHHVAIVVPF 189
               ...||...|.|.|              |:.::.| .|.:..||.:.|.:|.....||:::||
Human   131 PGLVGRLLIEFTSPMP--------------LERVQRE-NPGVLMGGRYTPPDCTPAQTVAVIIPF 180

  Fly   190 RDRYAHLLLFLRNIHPFLMKQRIAYRIFIVEQTNGKPFNRAAMMNIGYLEALKL-YQWDCFIFHD 253
            |.|..||..:|..:||.|.:||:.|.::::.|.....||||.::|:|:|||||. ..:|||||.|
Human   181 RHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDAAYDCFIFSD 245

  Fly   254 VDLLPLDDRNLYNCPRQPRHMSVAIDTLNFRLPYRSIFGGVSAMTREHFQAVNGFSNSFFGWGGE 318
            |||:|:||||||.|..||||.::|:|...|||||...|||||.:::..|..:|||.|.::|||||
Human   246 VDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGE 310

  Fly   319 DDDMSNRLKHANLFISRYPVNIARYKMLKHQKEK---ANPKRYENLQNGMSKIEQDGINSIKYSI 380
            |||:.||:....:.|||..:.|.||:|:||.::|   .||:|:..:||....:::|||.|::|.:
Human   311 DDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQV 375

  Fly   381 YSIKQFPTFT 390
            ..:.:.|.||
Human   376 LEVSRQPLFT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalNAcTA	NP_610946.1	b4GalT	181..395	CDD:132999	97/213 (46%)
B4GALT2	NP_085076.2	b4GalT	174..390	CDD:132999	97/211 (46%)