DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment beta4GalNAcTA and B4galt2

DIOPT Version :9

Sequence 1:	NP_610946.1	Gene:	beta4GalNAcTA / 36585	FlyBaseID:	FBgn0027538	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001101435.1	Gene:	B4galt2 / 313536	RGDID:	1305358	Length:	369	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	139/398 - (34%)
Similarity:	206/398 - (51%)	Gaps:	65/398 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RFLAG-------AICLLLVLNF-----VGFRSDGGSATSLSKLSIRRVHKYAH-IYGNASSDGAG 62
            |.|.|       |:.||.:|:|     :.|..........|:.|.|   ..|| :|..|||
  Rat     3 RLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSTR---SPAHALYPAASS---- 60

  Fly    63 GSEASRLPASPLALSKDRERDQELNGGPNSTIRTVIATANFTSIPQDLTRFLLGTKKFLPPRQKS 127
            .:..||                     ||:|    .|::....:|.              .|...
  Rat    61 STNCSR---------------------PNTT----AASSGLPEVPS--------------ARPGP 86

  Fly   128 TSALLANCTD-PDPRDGGPITPNTTLESLDVIEAELGPLLRPGGAFEPENCNAQHHVAIVVPFRD 191
            |:.::..|.| |....|..:...|:...|:.::.| .|.:..||.:.|.:|.....||:::|||.
  Rat    87 TAPVIPPCPDVPPGLVGRVVIEFTSPMPLERVQRE-NPGVLLGGRYSPPDCTPAQTVAVIIPFRH 150

  Fly   192 RYAHLLLFLRNIHPFLMKQRIAYRIFIVEQTNGKPFNRAAMMNIGYLEALKL-YQWDCFIFHDVD 255
            |..||..:|..:||.|.:||:.|.::::.|...:.||||.::|:|:|||||. ..:|||||.|||
  Rat   151 REHHLRYWLHYLHPMLRRQRLRYGVYVINQHGEETFNRAKLLNVGFLEALKEDATYDCFIFSDVD 215

  Fly   256 LLPLDDRNLYNCPRQPRHMSVAIDTLNFRLPYRSIFGGVSAMTREHFQAVNGFSNSFFGWGGEDD 320
            |:|:||||||.|..||||.::|:|...|||||.|.|||||.:::..|..:|||.|.::|||||||
  Rat   216 LVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDD 280

  Fly   321 DMSNRLKHANLFISRYPVNIARYKMLKHQKEK---ANPKRYENLQNGMSKIEQDGINSIKYSIYS 382
            |:.||:....:.|||..|.|.||:|:||.::|   .||:|:..:||....::.|||.|::|.:..
  Rat   281 DIFNRISLTGMKISRPDVRIGRYRMIKHDRDKHNEPNPQRFNKIQNTKMSMKWDGIGSVRYRVLE 345

  Fly   383 IKQFPTFT 390
            :.:.|.||
  Rat   346 VSRQPLFT 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalNAcTA	NP_610946.1	b4GalT	181..395	CDD:132999	100/214 (47%)
B4galt2	NP_001101435.1	b4GalT	142..358	CDD:132999	100/212 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342666
Domainoid	1	1.000	125	1.000	Domainoid score	I5331
eggNOG	1	0.900	-	-		E1_KOG3916
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2804
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3318
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201618at2759
OrthoFinder	1	1.000	-	-		FOG0002356
OrthoInspector	1	1.000	-	-		otm45920
orthoMCL	1	0.900	-	-		OOG6_103240
Panther	1	1.100	-	-	O	PTHR19300
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X405
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.760