DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8531 and Dnajc11

DIOPT Version :9

Sequence 1:	NP_610945.1	Gene:	CG8531 / 36584	FlyBaseID:	FBgn0033918	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001102164.1	Gene:	Dnajc11 / 362666	RGDID:	1307731	Length:	559	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	243/545 - (44%)
Similarity:	353/545 - (64%)	Gaps:	15/545 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SDAELD-ENYYTFLNLPRDATAEQINTAYRKQSRMFHPDKHLDPDSKKMAEIMFNRTKRAYEVLS 71
            |:.||| |:||:.||:.|:|:||::..|||:...::|||||.||:.|..||.:||...:||||||
  Rat     6 SEEELDNEDYYSLLNVRREASAEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLS 70

  Fly    72 DPQQRAIYDSVGEKGLRTEGWEILHRTKTPDEIREEYERLAQAAAERRLQQRTNPRGNITINVNA 136
            |||.|||||..|::||..||||::.|.:||.|||||:|||.:...||:|||||||:|.|::.|:|
  Rat    71 DPQTRAIYDIYGKRGLEMEGWEVVERKRTPAEIREEFERLQREREERKLQQRTNPKGTISVGVDA 135

  Fly   137 TEIFAPYDD-------SEMPHVEIGSMSIAQSIEAPITRKDMIIMSGNLYSSNGNGSGGFVIAGR 194
            |::|..||:       |..|.:||..|.|:||||||:|..|..|:||:|.:.||||.|....|.|
  Rat   136 TDLFDRYDEEYEDVSGSGFPQIEINKMHISQSIEAPLTATDTAILSGSLSTQNGNGGGSINFALR 200

  Fly   195 RLLN-KGWIELCAGAGN--GFLLGLKGGRTLSQKLTLNGGTNLNFRDQGVIPALFSTLAVQLDKH 256
            |:.: |||.||..|||:  |.|.|||..|.|:.:..:.....|.|..:|:.|.|.:.||..|||:
  Rat   201 RVTSAKGWGELEFGAGDLQGPLFGLKLFRNLTPRCFVTTNCALQFSSRGIRPGLTTVLARNLDKN 265

  Fly   257 TMGSLTLNAGSQSSMSTQIDHSKETYSLSSSLVIGTPHVYFGLSYTRKMM-ENELKLKLAAKVGT 320
            |:|.|....|.||:|:|.|....:|...:.:|.:|.||.:..:||..|.. :::.:||.:.|.|.
  Rat   266 TVGYLQWRWGIQSAMNTSIVRDTKTCHFTVALQLGIPHSFALISYQHKFQDDDQTRLKGSLKAGF 330

  Fly   321 FGFMGEYGVEKKVSKYSSVTATVSIGVPSGVILKFKILRSNQSYVFPIHLSDEIVPAAVFYASVT 385
            ||.:.|||.|:|:|::|.:.|.||||||.||.||.|:.|::|:|.|||||:|:::|:|||||:|.
  Rat   331 FGTIVEYGAERKISRHSVLGAAVSIGVPQGVSLKVKLNRASQTYFFPIHLTDQLLPSAVFYATVG 395

  Fly   386 PVIAWFFIKRTVMDPMEAERKNIEVERTKRQNEQRLSAKRHEASAAVHLMQATYNRIMTEELARN 450
            |::.:..:.|.::.|....:|..::|:.:......:..|:.||.|||.|||.:..||:..|.:|.
  Rat   396 PLVVYLAVHRLIIRPYLRAQKEKDLEKQRENTASDILQKKQEAEAAVRLMQESVRRIIEAEESRM 460

  Fly   451 GLIVTRAVYGCTLAGGRQFKPE--QSLDVTVAIQCMVKNGTLQLHDSSKSDLPGFYDPGIGEDKI 513
            |||:..|.|| .....:..|.|  :.:||||.:||:||:..|.|.::||:.|||||||.:||:|.
  Rat   461 GLIIVNAWYG-KFVNDKSRKNEKVKVIDVTVPLQCLVKDSKLILTEASKAGLPGFYDPCVGEEKS 524

  Fly   514 LRIEYTYQNQFEVIHIKDNEALRLP 538
            ||:.|.::.....:.:.|:||||:|
  Rat   525 LRVLYQFRGVLHQVMMPDSEALRIP 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8531	NP_610945.1	DnaJ	15..>91	CDD:223560	40/75 (53%)
		DnaJ	15..80	CDD:278647	35/64 (55%)
		DUF3395	409..538	CDD:288708	52/130 (40%)
Dnajc11	NP_001102164.1	DnaJ	14..79	CDD:278647	35/64 (55%)
		Selenoprotein_S	372..>447	CDD:284376	28/74 (38%)
		DUF3395	417..549	CDD:288708	52/132 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335781
Domainoid	1	1.000	270	1.000	Domainoid score	I1768
eggNOG	1	0.900	-	-		E2759_KOG0718
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14558
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1571
OMA	1	1.010	-	-		QHG55406
OrthoDB	1	1.010	-	-		D400850at33208
OrthoFinder	1	1.000	-	-		FOG0003651
OrthoInspector	1	1.000	-	-		oto96684
orthoMCL	1	0.900	-	-		OOG6_103676
Panther	1	1.100	-	-	LDO	PTHR44157
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3531
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770