DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8531 and l(3)80Fg

DIOPT Version :9

Sequence 1:NP_610945.1 Gene:CG8531 / 36584 FlyBaseID:FBgn0033918 Length:545 Species:Drosophila melanogaster
Sequence 2:NP_001015187.2 Gene:l(3)80Fg / 3354941 FlyBaseID:FBgn0287183 Length:780 Species:Drosophila melanogaster


Alignment Length:535 Identity:105/535 - (19%)
Similarity:186/535 - (34%) Gaps:173/535 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 YTFLNLPRDATAEQINTAYRKQSRMFHPDK-HLDPDSKKMAEIMFNRTKRAYEVLSDPQQRAIYD 80
            |..|.:.:.||..:|..||::.::.:|||| ..|..::|..:|     |.|||:|:|..:|.|:|
  Fly    32 YAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFIQI-----KLAYEILADLDRRRIFD 91

  Fly    81 SVGEKGLRTEGWEILHRTKTPDEIREEYERLAQAAAERRLQQRTNPRGNITINVNATEIFAPYDD 145
            ..|...:.::.::..|.       ..||.|                   .|:|.|..:....:|.
  Fly    92 RYGVSDINSQYFQKKHD-------YSEYNR-------------------FTLNQNDDDFGQRFDI 130

  Fly   146 SEMPHVEIGSMSIAQSIEAPITRKDMIIMSGNLYSSNGNGSGGFVIAGRRLLNKGWIELCAGAGN 210
            .:       .::..|.:.......:.:|:|.|....:       |:    :....|...|....:
  Fly   131 KQ-------DIAFYQKLSITENYFEKMILSKNAKKVH-------VV----MFYNDWCFKCTRIVD 177

  Fly   211 GFLLGLKGGRTLSQKLTLNGGTNLN-------FRDQGV--IPALFSTLAVQLDKHTMGSLT---- 262
            .|...|:    |.|.:.:|..| :|       ||..|.  :|.|...|..|...:...|.|    
  Fly   178 AFKKILE----LLQPIGINFAT-VNAVHEESVFRKCGAREVPQLVLILDNQYFLYRDHSFTPQKV 237

  Fly   263 ---LNAGSQSSMSTQIDHSKETYSLS------SSLVIGTPHVYFGLSYTRKMMENELKLKLAAKV 318
               :......::..:|:|......|.      :..:|..|.     |.||      |:..|.|  
  Fly   238 VEFIRKKIPFNVFKRIEHDNFNDFLGGWSDNRARALIFEPR-----SLTR------LRYLLTA-- 289

  Fly   319 GTFGFMGE--YGVEKKVSKYSS----------------------VTATVSI---GVPSGVILKFK 356
              |.|...  :|....:||.||                      .|.|.|:   .:|:.:::  .
  Fly   290 --FEFYDRVAFGFVNTISKDSSNIITRFKVNTSLDTLILFNEDTTTFTASVCMEEIPNHILV--N 350

  Fly   357 ILRSNQSYVFPIHLSDEI-------------------------------------VPAAVFYASV 384
            ::.:||...||...|..|                                     :..:|.|.|.
  Fly   351 MVSTNQFLAFPRISSQNIMESVCPTEWNRQRKHLCVILITENNRKKDFERVALRNIALSVGYNSE 415

  Fly   385 TPVIAWFFIKRTVMDPMEAERKN------IEVERTKRQNEQRLS------AKRHEASAAVHLMQA 437
            ....|:.| |.:..|.:::..|.      ||:....|::::|:.      ||::..|:..|||.:
  Fly   416 KVRFAYIF-KESQPDFIKSISKGSFKDSLIEIVIIWRRDKKRIKYNWVYVAKQNGNSSPEHLMNS 479

  Fly   438 TYNRI--MTEELARN 450
            |.::|  ..::|.:|
  Fly   480 TKDQISNAVKKLLKN 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8531NP_610945.1 DnaJ 15..>91 CDD:223560 24/74 (32%)
DnaJ 15..80 CDD:278647 22/63 (35%)
DUF3395 409..538 CDD:288708 13/50 (26%)
l(3)80FgNP_001015187.2 DnaJ 30..>94 CDD:223560 23/66 (35%)
DnaJ 30..91 CDD:278647 22/63 (35%)
TRX_DnaJ 134..244 CDD:239261 23/125 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45464391
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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