Protein Alignment Hsc70-5 and SSA4

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_011029.3
• Gene: SSA4 / 856840
• SGDID: S000000905
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 644
• Identity: 322/644 - (50%)
• Similarity: 425/644 - (65%)
• Gaps: 27/644 - (4%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            :|||||||.||:|.....:.::|.|.:|.|||||:|||| |.|||:|..||.||..|..||.:..
Yeast     5 VGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQAAMNPHNTVFDA 68

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            ||||||:||||||..|..:..:||:. ..|...|.   ..:.|.::|.:|.:.||.|||||||.:
Yeast    69 KRLIGRKFDDPEVTNDAKHYPFKVID-KGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENF 132

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDK--IIAVYD 244
            |.|.||:|||||||||||||||||||||.||||||||:||||||||:|||:||...|  .:.::|
Yeast   133 LGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFD 197

  Fly   245 LGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLK 309
            |||||||:|:|.|.:||||||:|.|||.|||||||:.:||||..|||:.:..|:..:..:::||:
Yeast   198 LGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLR 262

  Fly   310 EAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSD 372
            .|||:||..||||.||.|.:..|  .:|      ....:||::.|.|..||.:.|::|.:|.|:|
Yeast   263 TAAERAKRTLSSSAQTSIEIDSLFEGID------FYTSITRARFEELCADLFRSTLEPVEKVLAD 321

  Fly   373 AEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD----V 432
            :::.||:|.|::||||.||:||||..|.:.| |::|:||:|||||||.|||||..:|.||    .
Yeast   322 SKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTT 386

  Fly   433 TDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDN 497
            .|:|||||.||||||||.||:.|:||.||:|||||||:||||.:|.|..|.|:|.:|||....||
Yeast   387 QDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDN 451

  Fly   498 KLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIENM 561
            .|||.|.|.||||||||||||||.||||||||::|||.:|||||..:|.| ...|.|||::|:.|
Yeast   452 NLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKM 516

  Fly   562 IKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIADLRTLLAN 624
            :.:||::...|:|:.:.::..||.||.....:..:.|  ||.::..|:..||:....|....|..
Yeast   517 VAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDA 581

  Fly   625 KETADLEEVRKATSSLQQSS----LKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGE 679
            .:.|..||.::....|:..:    .|.:..|.....|.....||||.:.:..:..|..|
Yeast   582 SQAASTEEYKERQKELEGVANPIMSKFYGAAGGAPGAGPVPGAGAGPTGAPDNGPTVEE 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	318/629 (51%)
		HSPA9-like_NBD	51..428	CDD:212683	205/380 (54%)
		Syntaphilin	<566..>642	CDD:291936	19/77 (25%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	322/644 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810