Protein Alignment Hsc70-5 and SSE1

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_015219.1
• Gene: SSE1 / 855998
• SGDID: S000006027
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 716
• Identity: 192/716 - (26%)
• Similarity: 328/716 - (45%)
• Gaps: 124/716 - (17%)

  Fly    56 GIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATK 120
            |:|||..||.|||...:...::.|....|:|||.|.|... .|.:|...|.:..:|..||....|
Yeast     6 GLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPK-NRYLGETGKNKQTSNIKNTVANLK 69

  Fly   121 RLIGRRFDDPEVKKDITNLSYKVVKASN---GDAWVSSTDGKVYSPSQIGAFILMKMKETAEAYL 182
            |:||..:..|:.:::..:.:.|:|:..:   |.....:.:..|:|.:|:.|..:.|:|:|.:...
Yeast    70 RIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDT 134

  Fly   183 NTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-------DKII 240
            ...:.:..:.||.::.:.||....||.:|||||.:|::|:.|||.::||:.||:       .:|:
Yeast   135 KANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIV 199

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            |..|:|..::..||:..:||..:|..|..|...||.|||..|......|||....||||::..|.
Yeast   200 AFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAY 264

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKAL 370
            .|:..||||.|..||:    :.|.|:..........::.:|:|.:||.||..|::|..:|..|||
Yeast   265 NRILTAAEKLKKVLSA----NTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKAL 325

  Fly   371 SDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGA----AVQGGVLAGD 431
            :.|::|..|:..|.::||.||:|.::.::.|.||:..|.::|.|||:|.||    |:....|.
Yeast   326 AQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAFGKPLSTTLNQDEAIAKGAAFICAIHSPTLR-- 388

  Fly   432 VTDVLLLDVTPLSLG--------------IETLGGVF--TRLISRNTT---------------IP 465
            |......|:.|.|:.              :...|..|  |:||:.|.|               .|
Yeast   389 VRPFKFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPP 453

  Fly   466 TKKSQVFS------TASDGQTQVEIK---------VHQGEREMANDNKLLGSFTLVGIP-----P 510
            ....|:.:      ...:||..|.:|         :|..|.          ::|:..|.     |
Yeast   454 NTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEE----------AYTIEDIEVEEPIP 508

  Fly   511 APRGVPQ--------------------IEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSK 555
            .|...|:                    :...|.:||..:..:..|:.....:.::|.::..  .|
Yeast   509 LPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETED--RK 571

  Fly   556 DEIENMI-----KKAEEYA--TADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKK 613
            :.:|..|     |..||||  .:|.:|.:|..::|:.|..::|     |.|.| :.|:...|. :
Yeast   572 NTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGMLNKAEEWLYD-----EGFDS-IKAKYIAKY-E 629

  Fly   614 EIADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSG 678
            |:|.|..::..:..|..||.::|..|.|::| ::..:| :|::|:|::.|    .......||.|
Yeast   630 ELASLGNIIRGRYLAKEEEKKQAIRSKQEAS-QMAAMA-EKLAAQRKAEA----EKKEEKKDTEG 688

  Fly   679 E 679
            :
Yeast   689 D 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	189/701 (27%)
		HSPA9-like_NBD	51..428	CDD:212683	125/385 (32%)
		Syntaphilin	<566..>642	CDD:291936	23/77 (30%)
SSE1	NP_015219.1	HSP70	4..644	CDD:394970	177/663 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900