Protein Alignment Hsc70-5 and SSB2

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_014190.1
• Gene: SSB2 / 855512
• SGDID: S000005153
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 612
• Identity: 291/612 - (47%)
• Similarity: 394/612 - (64%)
• Gaps: 28/612 - (4%)

  Fly    48 GEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNS 112
            |..:|| ||||||||.||:|..| ...::|.|.:|.|.|||.||||.. |||:|..||.||..|.
Yeast     4 GVFQGA-IGIDLGTTYSCVATYE-SSVEIIANEQGNRVTPSFVAFTPQ-ERLIGDAAKNQAALNP 65

  Fly   113 ANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDA----WVSSTDGKVYSPSQIGAFILMK 173
            .||.:..||||||||||..|:||:....:||:.......    ::..|  |.:||.:|.|.:|.|
Yeast    66 RNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEET--KTFSPQEISAMVLTK 128

  Fly   174 MKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGM--DKTE 236
            |||.|||.:...|:.||:||||||||:|||||||||.|:||||||:||||||||:|||:  .|:|
Yeast   129 MKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSE 193

  Fly   237 -DKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRK 300
             ::.:.::||||||||:|:|.|..||:.||||:|:|.|||:|||.:::....|||||.:|:||..
Yeast   194 KERHVLIFDLGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISD 258

  Fly   301 DNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQP 365
            |..|::||:.|||:||..|||..||.:.:..| .|.   :.....|||::.|.|...|.|.|::|
Yeast   259 DARALRRLRTAAERAKRTLSSVTQTTVEVDSL-FDG---EDFESSLTRARFEDLNAALFKSTLEP 319

  Fly   366 CQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLA 429
            .::.|.||::|||:|.||:||||.||:||||..:.:.| |:|..:|:|||||||.||||||.:|.
Yeast   320 VEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILT 384

  Fly   430 GDVT-----DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQG 489
            |..|     |:|||||.|||||:...|.:|..::.||||:||.|.:.|:|.||.||.|:..|:||
Yeast   385 GQSTSDETKDLLLLDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQG 449

  Fly   490 EREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSS-GGL 553
            ||....:|.|||.|.|..||..|.|.|.:|.:|::|||||:.|:|.:|.|||...|.|.:: |.|
Yeast   450 ERVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRL 514

  Fly   554 SKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIA 616
            |.:|||.|:.:|||:..||:...:..|...:.||.|...|..:.:  ..|:|......|::..::
Yeast   515 SSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALS 579

  Fly   617 D-LRTLLANKETADLEEVRKATSSLQQ 642
            | |..|.....:||  |:|||...|::
Yeast   580 DALAALQIEDPSAD--ELRKAEVGLKR 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	290/609 (48%)
SSB2	NP_014190.1	PTZ00009	6..575	CDD:240227	280/577 (49%)