Protein Alignment Hsc70-5 and SSC1

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_012579.1
• Gene: SSC1 / 853503
• SGDID: S000003806
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 663
• Identity: 408/663 - (61%)
• Similarity: 523/663 - (78%)
• Gaps: 22/663 - (3%)

  Fly    23 SGASSMFRNLPGASNGISSQLRYKSGEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTP 87
            |..||.||        |:::|  :|.:|:|:|||||||||||.:|:||||..|:||||||:||||
Yeast    11 SSLSSSFR--------IATRL--QSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTP 65

  Fly    88 SHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAW 152
            |.|||||:||||||:|||||||.|..||.:||||||||||:|.||::||..:.||:||.||||||
Yeast    66 SVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAW 130

  Fly   153 VSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVL 217
            |.:. |:.|||:|||.|:|.||||||||||..|||||||||||||||||||||||||||.|||||
Yeast   131 VEAR-GQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVL 194

  Fly   218 RVINEPTAAALAYGMDKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHI 282
            ||:|||||||||||::|::.|::||:||||||||||||:|..||||||||||||.|||||||.::
Yeast   195 RVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYL 259

  Fly   283 VNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLT 347
            :..:|:.||.::|||:..|.:|:||::|||||||.||||:..|:||||::|.||:||:|:|:|.:
Yeast   260 LREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFS 324

  Fly   348 RSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVN 412
            |::.|:|...|:|||:.|.:|||.||.:|.|:|.||||||||:|||||..||:.|||:.||::||
Yeast   325 RAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVN 389

  Fly   413 PDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASD 477
            ||||||:||||||.||:|:|||||||||||||||||||||||||||.|||||||||||:||||:.
Yeast   390 PDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAA 454

  Fly   478 GQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKE 542
            |||.|||:|.|||||:..||||:|:|||.||||||:|||||||.|||||:||::|||:||.|.|:
Yeast   455 GQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKD 519

  Fly   543 QQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEE 607
            ..|.:..|.|||::|||.|:..||::.:.|:.:::.||..|:.:.:.:|||..::||:.::...|
Yeast   520 SSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAE 584

  Fly   608 CEKLKKEIADLRTLLA---NKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSD 669
            .:|::.:|..|:.|:|   ..|..:.||::..|..||.||:||||..||..|....:|.|
Yeast   585 AQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNG----- 644

  Fly   670 SSSSSDTSGEAKK 682
               ::..|||.|:
Yeast   645 ---NNAESGETKQ 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	395/617 (64%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	390/603 (65%)