Protein Alignment Hsc70-5 and SSE2

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_009728.1
• Gene: SSE2 / 852467
• SGDID: S000000373
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 708
• Identity: 199/708 - (28%)
• Similarity: 327/708 - (46%)
• Gaps: 112/708 - (15%)

  Fly    56 GIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATK 120
            |:|||..||.|||...:...|:.|....|:|||.|.| ....|.:|...|.:..:|..||....|
Yeast     6 GLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGF-GPRNRYLGESGKTKQTSNVKNTVENLK 69

  Fly   121 RLIGRRFDDPEVKKDITN--LSYKVVKASNGDAWVSSTDG---KVYSPSQIGAFILMKMKETAEA 180
            |:||.:|.|||.  ||.|  .:.|:|:..||...|....|   .|:|.:|:.|..:.|:|.|.:.
Yeast    70 RIIGLKFKDPEF--DIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQE 132

  Fly   181 YLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-------DK 238
            ...:.:.:..:.||.::::.||....||.:|||||.:|::|:.||||::||:.|.:       .:
Yeast   133 ETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPR 197

  Fly   239 IIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNI 303
            ||.:.|:|..|:..||:..:||..:|..|..|...||.|||..|......:||....|||||:..
Yeast   198 IIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPK 262

  Fly   304 AMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            |..|:..||||.|..||:    :...|:..........::.:|:|.:||.||..|:||...|...
Yeast   263 AYNRILIAAEKLKKVLSA----NTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITN 323

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGA----AVQGGVLA 429
            ||:.|:::.::|..|.::||.||:|.::.::.::||:..|.::|.|||||.||    |:....|.
Yeast   324 ALAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLR 388

  Fly   430 GDVTDVLLLDVTPLSLGIETLGGVFT-----------RLISRNTTIPTKKSQVFSTASDGQTQVE 483
              |......|:.|.|:.       :|           .:...|::.|:.|........|...:.
Yeast   389 --VRPFKFEDIDPYSVS-------YTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKA- 443

  Fly   484 IKVHQGEREMANDNKLL-GSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI 547
            :..|..:........:. .|||.|.:|.....:| ::|....|.:|: |:......|   :.|.:
Yeast   444 VYTHPSKLPKGTSTTIAKWSFTGVKVPKDQDFIP-VKVKLRCDPSGL-HIIENAYTT---EDITV 503

  Fly   548 QSSGGLSKD----------EIENMIKK------AEEYATADKQKRELIEIVNQ---GESIVHDTE 593
            |....|.:|          |:...|||      |:.:|....:..:|||..|:   .:.:|.:||
Yeast   504 QEPVPLPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETE 568

  Fly   594 TK---MEEFKSQLPAE------------ECEKLK--------------------------KEIAD 617
            .:   :||:...|.|:            |.||||                          :|:|.
Yeast   569 DRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELAS 633

  Fly   618 LRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSD 675
            |..::..:..|..||.|:|..:.|::| |:.::| :|::.:|.:.|.:..||.::..:
Yeast   634 LGNIIRGRYLAKEEEKRQALRANQETS-KMNDIA-EKLAEQRRARAASDDSDDNNDEN 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	197/697 (28%)
		HSPA9-like_NBD	51..428	CDD:212683	134/387 (35%)
		Syntaphilin	<566..>642	CDD:291936	25/119 (21%)
SSE2	NP_009728.1	HSP70	4..644	CDD:394970	185/659 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900