Protein Alignment Hsc70-5 and SSQ1

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_013473.1
• Gene: SSQ1 / 851084
• SGDID: S000004361
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 652
• Identity: 326/652 - (50%)
• Similarity: 460/652 - (70%)
• Gaps: 35/652 - (5%)

  Fly    39 ISSQLRYKSG-EVKGAVIGIDLGTTNSCLAVM----EGKQAKVIENAEGARTTPSHVAF------ 92
            |:|:|.|.:. ::...|||||||||||.:|.:    :.|.|.:|||.||.|||||.|||
Yeast    14 INSRLLYSTNPQLTKKVIGIDLGTTNSAVAYIRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSP 78

  Fly    93 -TKDG-ERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKA-SNGDAWVS 154
             .||. :.||||.||||...||.|||:||||||||.|:|.||::|:..:.||:||. |||.|::|
Yeast    79 QNKDQMKTLVGMAAKRQNAINSENTFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQAYLS 143

  Fly   155 STDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRV 219
            :::|.:.|||||.:.:|..:|:|:|.||...|..||:||||||||||||||||||::||||||||
Yeast   144 TSNGLIQSPSQIASILLKYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRV 208

  Fly   220 INEPTAAALAYGM-DKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIV 283
            |||||||||::|: ||..:.:||||||||||||||||:|:.|||||::|||||.||||||||.||
Yeast   209 INEPTAAALSFGIDDKRNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIV 273

  Fly   284 NFLVAEFKKD----SGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNL 344
            |:::..|..:    :..:|.|:...|||||:.:|:||.:||..::|.|.||::...    :|:.:
Yeast   274 NYIIDTFIHENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKS----KHLRV 334

  Fly   345 KLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSR 409
            .:|..:|:::...||.|||.|.::||.||::...:|.||:||||||||||::|.|::|||:.|:.
Yeast   335 PMTEEELDNMTLSLINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDLFGKSPNS 399

  Fly   410 SVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFST 474
            ||||||.||:|||:|||:|:|::.:|||||||||:|||||.||.|:.||.||||:|.||:::|||
Yeast   400 SVNPDETVALGAAIQGGILSGEIKNVLLLDVTPLTLGIETFGGAFSPLIPRNTTVPVKKTEIFST 464

  Fly   475 ASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGT 539
            ..|||..|:|||.||||.:..:|||:|...|.||.|.|:|:|||.|.|||||:||::|||.:|.:
Yeast   465 GVDGQAGVDIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQIYVTFDIDADGIINVSAAEKSS 529

  Fly   540 GKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLP 604
            ||:|.|.:..:.|||::||..:|::|......|...|:.:|::::.:.::.|||...:.::..:.
Yeast   530 GKQQSITVIPNSGLSEEEIAKLIEEANANRAQDNLIRQRLELISKADIMISDTENLFKRYEKLIS 594

  Fly   605 AE-ECEKLKKEIADLRTLLANKE------TADLEEVRKATSSLQQSSLKLFELAYKKMSAERESN 662
            :| |...:.::|..||..:.|.:      :.|:..::|||.:||..:||||:.|.|     .:.|
Yeast   595 SEKEYSNIVEDIKALRQAIKNFKANENDMSIDVNGIKKATDALQGRALKLFQSATK-----NQQN 654

  Fly   663 AG 664
            .|
Yeast   655 QG 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	322/639 (50%)
		HSPA9-like_NBD	51..428	CDD:212683	218/394 (55%)
		Syntaphilin	<566..>642	CDD:291936	17/82 (21%)
SSQ1	NP_013473.1	dnaK	29..656	CDD:234715	321/635 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S115
OMA	1	1.010	-	-		QHG61239
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100423
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730