Protein Alignment Hsc70-5 and SSA2

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_013076.1
• Gene: SSA2 / 850636
• SGDID: S000003947
• Length: 639
• Species: Saccharomyces cerevisiae
• Alignment Length: 650
• Identity: 310/650 - (47%)
• Similarity: 418/650 - (64%)
• Gaps: 38/650 - (5%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            :|||||||.||:|.....:..:|.|.:|.|||||.|.|| |.|||:|..||.||..|.|||.:..
Yeast     5 VGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFT-DTERLIGDAAKNQAAMNPANTVFDA 68

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDGKV------------YSPSQIGAFILM 172
            ||||||.|:||||:.|:.:..:|::          ..|||.            ::|.||.:.:|.
Yeast    69 KRLIGRNFNDPEVQGDMKHFPFKLI----------DVDGKPQIQVEFKGETKNFTPEQISSMVLG 123

  Fly   173 KMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT-E 236
            |||||||:||...|.:|||||||||||||||||||||.||||||||:||||||||:|||:||. :
Yeast   124 KMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGK 188

  Fly   237 DKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKD 301
            ::.:.::||||||||:|:|.|:.|:||||:|.|||.||||||||.:||..:.|||:.:..|:..:
Yeast   189 EEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTN 253

  Fly   302 NIAMQRLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQ 364
            ..|::||:.|.|:||..||||.||.:.:..|  .:|      ....:||::.|.|..||.:.|:.
Yeast   254 QRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGID------FYTSITRARFEELCADLFRSTLD 312

  Fly   365 PCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVL 428
            |.:|.|.||::.||::.|::||||.||:||||..|.:.| |::|:||:|||||||.|||||..:|
Yeast   313 PVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAIL 377

  Fly   429 AGD----VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQG 489
            .||    ..|:|||||.||||||||.|||.|:||.||:|||||||:||||.:|.|..|.|:|.:|
Yeast   378 TGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEG 442

  Fly   490 EREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGL 553
            ||....||.|||.|.|.||||||||||||||.||:|:|||::|||.:|||||..:|.| ...|.|
Yeast   443 ERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRL 507

  Fly   554 SKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADL 618
            ||::||.|:.:||::...|:::.:.|...||.|||.:..:..:.|...:|...:.:.:.|:..:.
Yeast   508 SKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAGDKLEQADKDAVTKKAEET 572

  Fly   619 RTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGEAKKE 683
            ...|.:..||..||.......||:.:..:....|:...|...:..|.....:..:.:..|...:|
Yeast   573 IAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGAPPAPEAEGPTVEE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	308/631 (49%)
SSA2	NP_013076.1	PTZ00009	4..639	CDD:240227	309/649 (48%)