DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc70-5 and BIP1

DIOPT Version :9

Sequence 1:	NP_001286414.1	Gene:	Hsc70-5 / 36583	FlyBaseID:	FBgn0001220	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_198206.1	Gene:	BIP1 / 832950	AraportID:	AT5G28540	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	642	Identity:	315/642 - (49%)
Similarity:	428/642 - (66%)	Gaps:	27/642 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTF 116
            |:|||||||||.||:.|.:....::|.|.:|.|.|||.|.|| |.|||:|..||.||..|...|.
plant    35 GSVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFT-DSERLIGEAAKNQAAVNPERTV 98

  Fly   117 YATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAW--VSSTDG--KVYSPSQIGAFILMKMKET 177
            :..||||||:|:|.||:||...:.|::|. .:|..:  |...||  ||:||.:|.|.||.|||||
plant    99 FDVKRLIGRKFEDKEVQKDRKLVPYQIVN-KDGKPYIQVKIKDGETKVFSPEEISAMILTKMKET 162

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT-EDKIIA 241
            |||||...:|:|||||||||||:|||||||||.||||||.|:||||||||:|||:||. .:|.|.
plant   163 AEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNIL 227

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            |:||||||||:|:|.|..|||||.||||||.|||||||:.::.:.:...||....||.|||.|:.
plant   228 VFDLGGGTFDVSVLTIDNGVFEVLSTNGDTHLGGEDFDHRVMEYFIKLIKKKHQKDISKDNKALG 292

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKA 369
            :|:...|:||..|||..|..:.:..|  .:|.:.|      |||::.|.|..||.::|:.|.:||
plant   293 KLRRECERAKRALSSQHQVRVEIESLFDGVDFSEP------LTRARFEELNNDLFRKTMGPVKKA 351

  Fly   370 LSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG--- 430
            :.||.:.||:|.|::||||.||:||||..:::.| |::|::.||||||||.|||||||:|:|
plant   352 MDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDFFEGKEPNKGVNPDEAVAYGAAVQGGILSGEGG 416

  Fly   431 -DVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMA 494
             :..|:|||||.||:|||||:|||.|:||.|||.|||||||||:|..|.||.|.|:|.:|||.:.
plant   417 DETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLT 481

  Fly   495 NDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEI 558
            .|.:|||.|.|.||||||||.|||||.|::|||||::|.|:||.:||.::|.| ...|.||::||
plant   482 KDCRLLGKFDLNGIPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKGRLSQEEI 546

  Fly   559 ENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKM---EEFKSQLPAEECEKLKKEIADLRT 620
            :.|:|:|||:|..||:.:|.|:..|..|:.|::.:.::   ::...:|..:|.||::....:...
plant   547 DRMVKEAEEFAEEDKKVKEKIDARNALETYVYNMKNQVNDKDKLADKLEGDEKEKIEAATKEALE 611

  Fly   621 LLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTS 677
            .|...:.::.||..:....::.....:....|::...   :..|||...|:...|.|
plant   612 WLDENQNSEKEEYDEKLKEVEAVCNPIITAVYQRSGG---APGGAGGESSTEEEDES 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	310/629 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	207/383 (54%)
		Syntaphilin	<566..>642	CDD:291936	17/78 (22%)
BIP1	NP_198206.1	PTZ00009	35..644	CDD:240227	308/616 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820