Protein Alignment Hsc70-5 and hspa1b

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 640
• Identity: 320/640 - (50%)
• Similarity: 416/640 - (65%)
• Gaps: 36/640 - (5%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..||||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
Zfish     3 KGLSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKET 177
            .:..||||||:|||..|:.|:....:||: :.:|...|.   ..:.|.:.|.:|.:.:|:||:|.
Zfish    67 IFDAKRLIGRKFDDQVVQSDMKLWPFKVI-SEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREI 130

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE--DKII 240
            |||||...|.|||:||||||||||||||||||.||||||||:||||||||:|||:||..  ::.:
Zfish   131 AEAYLGHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNV 195

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            .::||||||||:|||.|:.|:||||:|.|||.||||||||.:|...|.|||:....||.::..|:
Zfish   196 LIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAV 260

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            :||:.|.|:||..||||.|..|.:..|  .:|      ....:||::.|.|..:|.:.|:.|.:|
Zfish   261 RRLRTACERAKRTLSSSSQASIEIDSLFEGID------FYTSITRARFEELNAELFRGTLDPVEK 319

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD- 431
            ||.||::.||:|.:::||||.||:||:|..:|:.| ||..::|:|||||||.|||||..:|.||
Zfish   320 ALRDAKMDKSQIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDT 384

  Fly   432 ---VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREM 493
               |.|:|||||.||||||||.|||.|.||.||||||||::|:|||.||.|..|.|:|.:|||.|
Zfish   385 SENVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAM 449

  Fly   494 ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDE 557
            ..||.|||.|.|.||||||||||||||.||||||||::|||.||.||||.:|.| ...|.|||::
Zfish   450 TKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKED 514

  Fly   558 IENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRT-- 620
            ||.|::.||:|...|:.:||.|...|..||.....:..:|:  ..|..:..|:.||:|.|..|
Zfish   515 IERMVQDAEKYKAEDEVQREKIAAKNALESYAFSMKNTVED--ENLRGKISEQDKKKIIDKCTEV 577

  Fly   621 --LLANKETADLEEVRKATSSLQQSSLKLFELAYK---------KMSAERESNAG 664
              .|.|.:.|:.||.......|:.....:....|:         ...|:.||:.|
Zfish   578 VSWLENNQLAEKEEYEHHQKELESVCNPIISRLYQGGAPPAGGCGFQAQPESSQG 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	320/640 (50%)
		HSPA9-like_NBD	51..428	CDD:212683	198/384 (52%)
		Syntaphilin	<566..>642	CDD:291936	23/79 (29%)
hspa1b	NP_001093532.1	HSP70	1..639	CDD:331774	320/640 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920