Protein Alignment Hsc70-5 and hspa1l

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001072429.1
• Gene: hspa1l / 779883
• XenbaseID: XB-GENE-6045069
• Length: 639
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 317/626 - (50%)
• Similarity: 427/626 - (68%)
• Gaps: 38/626 - (6%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..||||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
 Frog     4 KGVAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPHNT 67

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKET 177
            .:..||||||::|:|.|:.|:.:..:||: :..|...|:   ..:||.:||.:|.:.:|.|||||
 Frog    68 VFDAKRLIGRKYDEPVVQSDMKHWPFKVI-SDGGKPKVTVEYKGEGKSFSPEEISSMVLTKMKET 131

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKII 240
            |||||...|.|||:||||||||||||||||||.||||||||:||||||||:|||:||:  .::.|
 Frog   132 AEAYLGYKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKSGRGERNI 196

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            .::||||||||:|||.|..|:||||:|.|||.||||||||.:||..|.|||:....||..:..|:
 Frog   197 LIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNCMVNHFVEEFKRKHKKDISPNKRAL 261

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            :||:.|.|:||..||||.|..|.:..|  .:|      ....:||::.|.|..||.:.|::|.:|
 Frog   262 RRLRTACERAKRTLSSSTQASIEIDSLFEGID------FYTSITRARFEELCADLFRGTLEPVEK 320

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD- 431
            |:.||::.||:|.|::||||.||:||||..:|:.| |::.::|:|||||||.|||||..:|.||
 Frog   321 AMRDAKLDKSQIHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILMGDK 385

  Fly   432 ---VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREM 493
               |.|:|||||.|||||:||.|||.|.||.||||||.|::|.|:|.||.|..|.|:|::|||.|
 Frog   386 SENVQDLLLLDVAPLSLGLETAGGVMTVLIKRNTTIPIKQTQTFTTYSDNQPGVLIQVYEGERAM 450

  Fly   494 ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDE 557
            ..||.|||.|.|.||||||||||||||.||||||||::|||.||.:||:.:|.| ...|.|||:|
 Frog   451 TKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSSGKKNKITITNDKGRLSKEE 515

  Fly   558 IENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLL 622
            ||.|:::|::|...|:|:||.|...|..||...:.::.:|:          ..:|.:|:|
 Frog   516 IERMLQEADKYKADDEQQREKIAAKNSLESYAFNMKSTVED----------NNIKDKISD----- 565

  Fly   623 ANKETADLEEVRKATSSLQQSSL-KLFELAYKKMSAERESN 662
            ::|::. |::.::..|.|:|:.| :..|..:|:...|:..|
 Frog   566 SDKKSI-LDKCQEVISWLEQNQLAEKEEYTHKQKELEKLCN 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	317/626 (51%)
		HSPA9-like_NBD	51..428	CDD:212683	204/384 (53%)
		Syntaphilin	<566..>642	CDD:291936	17/75 (23%)
hspa1l	NP_001072429.1	HSP70	2..639	CDD:331774	317/626 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920