Protein Alignment Hsc70-5 and hspa12a

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_017207164.1
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 671
• Species: Danio rerio
• Alignment Length: 703
• Identity: 147/703 - (20%)
• Similarity: 251/703 - (35%)
• Gaps: 225/703 - (32%)

  Fly    54 VIGIDLGTTNSCLAVMEGKQAKVIENA---EGA------RTTPSHVAFTKDGERLVGMPAKRQAV 109
            |:.||.|||:|..|....|:.:.|...   ||.      :.||:.:..|.|        .|..:.
Zfish    56 VVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTPD--------KKFHSF 112

  Fly   110 TNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNG----DAWVSSTDGKVYSPSQIGAFI 170
            ..:|..||       ...|..|.|:.:....:|:...:..    |..:.:.:||......|.|:.
Zfish   113 GYAARDFY-------HDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVKALDIFAYA 170

  Fly   171 LMKMKETAEAYLN----TPVKNA----VVTVPAYFNDSQRQATKDAGQIAGL------NVLRVIN 221
            |...||.|...|:    ....||    |:||||.:....:|..::|...|.|      :.|.:..
Zfish   171 LAFFKEQALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIAL 235

  Fly   222 EPTAAAL----------------------------AYGMDKTEDKI------------------- 239
            ||.||::                            ..||.:.::.:
Zfish   236 EPEAASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELW 300

  Fly   240 --------IAVYDLGGGTFDISILEIQ------KGVFEVKSTNG-----------DTLL---GGE 276
                    ..|.|.||||.|:::.:|:      |.::  |::.|           :.||   .|:
Zfish   301 SELAEGDRYVVVDCGGGTVDLTVHQIRLPEGHLKELY--KASGGPYGSIGIDYEFEKLLCKIFGQ 363

  Fly   277 DFDNHIVNFLVAEFK---KDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMD--- 335
            ||        :.:||   ..:.:|:.   ||.:..|.||...:     |...:||||:..:|
Zfish   364 DF--------IDQFKIKRPAAWVDLM---IAFESRKRAATPDR-----SNPLNINLPFSFIDYYK 412

  Fly   336 ---AAGPQHM---------------NLKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGE 382
               ....:|.               .|:::...:.:|....|...||...:.....||  ::|..
Zfish   413 KFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTELFDRPEV--TDIKF 475

  Fly   383 VLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAV-QGGVLAGDVTDVLLLDVTPLSL 445
            :.||||....|.:|..||.:. ||  ||.:.|.:   ||..: :|.||.|....::.:..:||:.
Zfish   476 LFLVGGFAESPLLQQAVQNMLQGR--SRIIIPHD---VGLTILKGAVLFGLDPSIIKVRRSPLTY 535

  Fly   446 GIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQ---TQVEIKVHQGEREMANDNKLLGSFTLVG 507
            |:    ||..|.:....  |.:|..|    .||.   |.|.......::.:|....:..|:|
Zfish   536 GV----GVLNRFVEGKH--PPEKMLV----KDGMRWCTDVFDTFISADQSVALGETVKRSYT--- 587

  Fly   508 IPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSK-DEIENMIKKAEEYATA 571
              ||.   |..:|:       ::||...:|     :.:...:..|:.| ..::..:...|..|.
Zfish   588 --PAK---PSQQVI-------VIHVYCSEK-----ESVTFITDPGVRKCGSLKLDVSGTESPAA- 634

  Fly   572 DKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLAN 624
               :||:..::..|     |||.:              .:..::|..||:.|:
Zfish   635 ---RREIQTLMQFG-----DTEIR--------------AMAVDVATSRTVKAS 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	147/703 (21%)
		HSPA9-like_NBD	51..428	CDD:212683	107/501 (21%)
		Syntaphilin	<566..>642	CDD:291936	12/59 (20%)
hspa12a	XP_017207164.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900