Protein Alignment Hsc70-5 and hspa8b

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 651
• Identity: 311/651 - (47%)
• Similarity: 419/651 - (64%)
• Gaps: 35/651 - (5%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..:|||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
Zfish     3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPTNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDI---------TNLSYKVVKASNGDAWVSSTDGKVYSPSQIGAFIL 171
            .:..||||||||||..|:.|:         .||..||.....|:.       |.:.|.::.:.:|
Zfish    67 VFDAKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGET-------KTFYPEEVSSMVL 124

  Fly   172 MKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT- 235
            .||||.|||||...:.|||:||||||||||||||||||.|:||||||:||||||||:|||:||.
Zfish   125 TKMKEIAEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKV 189

  Fly   236 -EDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIR 299
             .::.:.::||||||||:|||.|:.|:||||||.|||.||||||||.:|...::|||:....||.
Zfish   190 GSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDIS 254

  Fly   300 KDNIAMQRLKEAAEKAKCELSSSQQTDINLP--YLTMDAAGPQHMNLKLTRSKLESLVGDLIKRT 362
            .:..|::||:.|.|:||..||||.|..|.:.  |..:|      ....:||::.|.|..||.:.|
Zfish   255 DNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGT 313

  Fly   363 IQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGG 426
            :.|.:|:|.||::.||::.:::||||.||:||:|..:|:.| |::.::|:|||||||.|||||..
Zfish   314 LDPVEKSLRDAKLDKSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAA 378

  Fly   427 VLAGD----VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVH 487
            :|.||    |.|:||||||||||||||.|||.|.||.||||||||::|.|:|..|.|..|.|:|:
Zfish   379 ILCGDKSENVQDLLLLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVY 443

  Fly   488 QGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSG 551
            :|||.|..||.|||.|.|.||||||||||||||.||||||||::|||.||.||||.:|.| ...|
Zfish   444 EGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKG 508

  Fly   552 GLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKE 614
            .|||::||.|:::||:|...|..:||.:...|..||...:.::.:|:  .|.::..|:.:|:..:
Zfish   509 RLSKEDIERMVQEAEKYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINK 573

  Fly   615 IADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGE 679
            ..::.:.|...:||:.||.......|::....:....|:......|...|.|...:..:....|.
Zfish   574 CNEVISWLDKNQTAEKEEFEHQQKELEKLCNPIITKLYQGTGGMPEGMPGGGFPGAGGAPGGGGS 638

  Fly   680 A 680
            :
Zfish   639 S 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	309/635 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	195/390 (50%)
		Syntaphilin	<566..>642	CDD:291936	18/77 (23%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	307/623 (49%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	193/387 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820