Protein Alignment Hsc70-5 and hspa12a.3

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 632
• Identity: 148/632 - (23%)
• Similarity: 253/632 - (40%)
• Gaps: 153/632 - (24%)

  Fly    55 IGIDLGTTNSCLAV-MEGKQAKVIENAE--------GART--TPS------HVAFTKDGERLVGM 102
            |.||.||:.|..|: .:.||.:  |:.:        |..|  ||:      |..|.|.|...:
Zfish     8 IAIDFGTSYSGYAISFKTKQPQ--ESIQIPNWGVNFGYNTFKTPTCILFDEHETFQKFGYDAM-- 68

  Fly   103 PAKRQAVTNSANTFYATKRLIGRRFD----DPEVKKDITNLSYKVVKASNGDAWVSSTDGKVYSP 163
                ...|.|.....|.|..:...|.    |.|:.:|:      ::.|.||....:.|   |:|.
Zfish    69 ----MTYTRSTPKSQARKSFLFEHFKMELYDKEIHRDL------MITAKNGGQMKALT---VFSE 120

  Fly   164 S--QIGAFILMKMKE--TAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNV------LR 218
            |  .:....|.|:||  |.:.::.:.| ..|:||||.:|.:.:|..::|...|||.:      |.
Zfish   121 SLRYLKDHALEKIKENTTGKTFIASDV-TWVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLV 184

  Fly   219 VINEPTAAAL------AYG-------MDKTEDK---IIAVYDLGGGTFDISILEIQKG--VFEVK 265
            ...||.||::      :.|       .|..|.|   ...|.|.||||.||::.|:.:.  :.|:.
Zfish   185 FALEPEAASIYCKQLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELN 249

  Fly   266 STNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTD---- 326
            :.:|:. :||:..|...::||...|.:      :..|...|.....|.|.|.:::.::..|
Zfish   250 AASGND-MGGQTVDRKFISFLKEIFSE------KIYNKFEQDFPAEALKLKYDIALAKSCDQLVL 307

  Fly   327 INLPYLTMDAAGPQHM----------------NLKLTRSKLESLVGDLIKRTIQPCQKALSDAEV 375
            |..|....|.|..:..                ::.:...||:|...:.:|.|.:..:|.:|:.|:
Zfish   308 IQCPVTLQDLAKKEKAIESYFEGVEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPEL 372

  Fly   376 SKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDV 440
            :   |..:|||||......::..::|.|.:  .:.|.|.|...|  .::|.:.......|:...:
Zfish   373 N---IEYMLLVGGFAECKILKKFLKERFDK--CKIVCPVEPQVV--IIKGAIRYAKQPKVVKSRM 430

  Fly   441 TPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEI----KVHQGE-------REM- 493
            :.|:.||. :...|.:::.:.     |.|.|   .|:|||..::    .|.:||       |:.
Zfish   431 SALTYGIR-IDAPFDKVLHKG-----KTSYV---NSEGQTYCDVCFETFVRKGESVNCDEVRQFF 486

  Fly   494 ---ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSK 555
               ::.|:...:|...       ...:.:|.| ||..|:..|.....|..|       :.||||:
Zfish   487 FNPSDTNQTFATFQFF-------STNEKQVQF-IDEPGVESVGVFQVGMPK-------TDGGLSR 536

  Fly   556 D-EIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKS 601
            : ::|......|..|||..        |:.||:    |..|::...|
Zfish   537 EIKLEIKFGSTEMKATATD--------VDSGET----TSVKLDFINS 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	148/632 (23%)
		HSPA9-like_NBD	51..428	CDD:212683	107/441 (24%)
		Syntaphilin	<566..>642	CDD:291936	10/36 (28%)
hspa12a.3	NP_001038346.3	HSPA12_like_NBD	6..420	CDD:212671	107/443 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900