DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc70-5 and hspa13

DIOPT Version :9

Sequence 1:	NP_001286414.1	Gene:	Hsc70-5 / 36583	FlyBaseID:	FBgn0001220	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001017223.1	Gene:	hspa13 / 549977	XenbaseID:	XB-GENE-963595	Length:	476	Species:	Xenopus tropicalis

Alignment Length:	427	Identity:	146/427 - (34%)
Similarity:	233/427 - (54%)	Gaps:	55/427 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VIGIDLGTTNSCLAVME--GKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTF 116
            |||||||||...:.|..  ..:.:||.:..|.::.||.|:|| :.:..||......|..|..||.
Frog    33 VIGIDLGTTYCSVGVFHPGTGEVRVITDENGHQSIPSIVSFT-EKDVFVGYDGLELADANPQNTI 96

  Fly   117 YATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAW--VSSTDGKVYSPSQIGAFILMKMKETAE 179
            |..||.||:.|...|::|:.....:||:. .|||.:  ||:.:....:|..|.:.:|:|:|:.||
Frog    97 YDAKRFIGKIFTQEELEKESVRYQFKVLN-RNGDVFFSVSTNETFAVTPEYISSQLLLKLKKMAE 160

  Fly   180 AYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKIIAVYD 244
            .||..||..||::|||.|::.||..|..|..:|||::|||||||||||:|||:.|.:...:.|.|
Frog   161 DYLGLPVSKAVISVPAEFDERQRNYTVKAANLAGLDILRVINEPTAAAMAYGLHKVDVFNVLVVD 225

  Fly   245 LGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAE-FKKDSGIDIRKDNIAMQRL 308
            |||||.|:|:|..|.|:|..::..|:..|||:||:..::.:|..: :.:...:..:|:.|  .||
Frog   226 LGGGTLDVSLLNKQGGMFLTRAMAGNNKLGGQDFNQRLLQYLYDKIYTRYGSVPSQKEEI--HRL 288

  Fly   309 KEAAEKAKCELSSSQQTDINLPYLTM------------------------------------DAA 337
            ::|.|..|..|:....:.:.:| ||:                                    .::
Frog   289 RQAVEAIKLNLTLHNSSWVRMP-LTLASTHPDSSKPDKIIPNESLENTGEIHPKSAHLGDSYSSS 352

  Fly   338 GPQHMN---------LKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMP 393
            |||..|         :::||...|:|..||.::.:.|.::.|.:..|.|.|:.|::||||.||:|
Frog   353 GPQIQNKHAEKVYFEMEITRHIFETLNEDLFQKILIPVEQVLKEGHVLKEEVDEIVLVGGSTRIP 417

  Fly   394 KVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAG 430
            :::..:::.||:.|:.||:||.||..|.|:|.|::.|
Frog   418 RIRQVIRDFFGKDPNTSVDPDLAVVTGVAIQAGIMGG 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	146/427 (34%)
		HSPA9-like_NBD	51..428	CDD:212683	145/423 (34%)
		Syntaphilin	<566..>642	CDD:291936
hspa13	NP_001017223.1	HSPA13-like_NBD	23..468	CDD:212679	146/427 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010