Protein Alignment Hsc70-5 and Hspa14

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 523
• Identity: 152/523 - (29%)
• Similarity: 270/523 - (51%)
• Gaps: 45/523 - (8%)

  Fly    53 AVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFY 117
            |.||:.||.|::|:||.:..:|.|:.|..|.|.||:.||:: :.|::||:.||:..:.:.::|..
Mouse     2 AAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYS-EREQVVGLAAKQSRIRHVSSTVV 65

  Fly   118 ATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDG---KVYSPSQIGAFILMKMKETAE 179
            ..|:::||...||:.:|.|:.....|:: .||........|   |:.:|..:...|..||||||.
Mouse    66 KVKQILGRSSADPQAQKYISESKCLVIE-KNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAH 129

  Fly   180 AYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK---TEDKIIA 241
            :.|.:...:.|||||..|.:.|:.|..:|...||.||||:|:||:||.||||:.:   |....:.
Mouse   130 SVLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVL 194

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            |:.|||.:..:|::|:..|::.|.|||....:||..|.:.:..:|.:||::....|:|.:..||.
Mouse   195 VFKLGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMM 259

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYLTMDAAG--------PQHMNLKLTRSKLESLVGDLIKRTI 363
            :|..:||.||..||            |:.:|.        .|..:..::|::.|.|...|..:..
Mouse   260 KLMNSAEVAKHSLS------------TLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCT 312

  Fly   364 QPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPS----RSVNPDEAVAVGAAVQ 424
            :..::.|.....:..:|.:|:|.||.:|:||:|..:::||   |:    .|:.|||.:.:|||::
Mouse   313 EAIRELLRQTGFTADDINKVVLCGGSSRIPKLQQLIKDLF---PAVDLLNSIPPDEVIPIGAAIE 374

  Fly   425 GGVLAGDVT----DVLLLDVTP---LSLGIETLGG-VFTRLISRNTTIPTKKSQVFSTASDGQTQ 481
            .|:|.|..:    |.::::.:.   |..|::..|. .||.|....|.:|.::..... |....:.
Mouse   375 AGILVGKESTSGDDSVMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQ-APGRVSS 438

  Fly   482 VEIKVHQGE-REMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQI 545
            |.:::::.| :..|.:........|..:.....|:..|..|..:..:|.:.|:..|:.|||.:.|
Mouse   439 VCLELYESEGKNSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAI 503

  Fly   546 VIQ 548
            .::
Mouse   504 TVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	152/523 (29%)
Hspa14	NP_056580.2	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	126/392 (32%)