Protein Alignment Hsc70-5 and Hsp70Bbb

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 316/648 - (48%)
• Similarity: 427/648 - (65%)
• Gaps: 48/648 - (7%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            ||||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|.|||.|...|..||.:..
  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            ||||||::|||::.:|:.:..:||| :..|...:.   ..:.|.::|.:|.:.:|.|||||||||
  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVV-SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKIIAVYD 244
            |...:.:||:||||||||||||||||||.||||||||:||||||||||||:||.  :::.:.::|
  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLIFD 196

  Fly   245 LGGGTFDISILEIQKG-VFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRL 308
            |||||||:|||.|.:| :|||:||.|||.||||||||.:|..|..|||:....|:|.:..|::||
  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261

  Fly   309 KEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDA 373
            :.|||:||..||||.:..|.:..|...    |....|::|::.|.|..||.:.|:||.:|||:||
  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEG----QDFYTKVSRARFEELCADLFRNTLQPVEKALNDA 322

  Fly   374 EVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD----VT 433
            ::.|.:|.:::||||.||:|||||.:||.| |:..:.|:|||||||.|||||..:|:||    :.
  Fly   323 KMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQ 387

  Fly   434 DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNK 498
            ||||:||.||||||||.|||.|:||.||..||.|:::.|||.||.|..|.|:|::|||.|..||.
  Fly   388 DVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNN 452

  Fly   499 LLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQS-SGGLSKDEIENMI 562
            .||:|.|.||||||||||||||.||:|||||::||||:..|||.:.|.|:: .|.||:.||:.|:
  Fly   453 ALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMV 517

  Fly   563 KKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPA---EECEK---LKKEIADLRTL 621
            .:||:||..|::.|:.|...|..||.|.:.:..:|    |.||   :|.:|   |.|....:|.|
  Fly   518 NEAEKYADEDEKHRQRITSRNALESYVFNVKQSVE----QAPAGKLDEADKNSVLDKCNETIRWL 578

  Fly   622 ----LANKETAD--LEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSG 678
                .|.||..|  :||:.:..|.:              |:...:..|||.....::....:|
  Fly   579 DSNTTAEKEEFDHKMEELTRHCSPI--------------MTKMHQQGAGAAGGPGANCGQQAG 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	314/634 (50%)
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	316/648 (49%)