Protein Alignment Hsc70-5 and Hsc70-2

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 640
• Identity: 298/640 - (46%)
• Similarity: 418/640 - (65%)
• Gaps: 33/640 - (5%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            ||||||||.||:.|.:..:.::|.|.:|.|||||:||| .:.|||:|.|||.|...|:.||.:..
  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF-NETERLIGDPAKNQVAMNAKNTVFDA 70

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            ||||||:|||.::::|:....:||:. ..|...:.   ..:.|.::|.:|.:.:|.||:|.||.|
  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVIN-EKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVY 134

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKIIAVYD 244
            |...||:|||||||||||||||||||||.||||||||:||||||||||||:||.  .::.:.::|
  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199

  Fly   245 LGGGTFDISILEIQKG-VFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRL 308
            |||||||:|:|.|.:| :||||:|.|||.||||||||.:||....|||:....||:.:..|::||
  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264

  Fly   309 KEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNL----KLTRSKLESLVGDLIKRTIQPCQKA 369
            :.|.|:||..||||.:..:.:..|        |..:    |::|::.|.|..||.:.|:||.::|
  Fly   265 RTACERAKRTLSSSTEASLEIDAL--------HEGIDFYSKISRARFEELNMDLFRSTMQPVERA 321

  Fly   370 LSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG--- 430
            ||||::.|..|.:|:||||.||:||:|..:|:|| |:|.:.|:|||||||.|||||..:|.|
  Fly   322 LSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGS 386

  Fly   431 -DVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMA 494
             .:.|:||:||.||||||||.|||.|.|:.||..||.|:.|:|:|.||.|..|.|:|::|||.|.
  Fly   387 SQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMT 451

  Fly   495 NDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQS-SGGLSKDEI 558
            .||.|||:|.|.||||||||||||||.||::|:||::|:|||..|||.::|.|.: .|.|||.||
  Fly   452 KDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEI 516

  Fly   559 ENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAE-ECEKLKKEIADLRTLL 622
            :.|:.:||:|...|.::||.::..|..|:.::.....:::..|.:.:| |..|::.:.:...:.|
  Fly   517 DRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWL 581

  Fly   623 ANKETADLEEVRKATSSLQQSSLKLFELAY--KKMSAERESNAGAGSSDSSSSSD 675
            .....|:.||........|:....:....:  ||    .:|:.|.||..:....|
  Fly   582 DKNSLAEKEEFESHLKECQRICTPIMSKIHGGKK----GKSSMGKGSHPTVEEVD 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	295/629 (47%)
		HSPA9-like_NBD	51..428	CDD:212683	194/383 (51%)
		Syntaphilin	<566..>642	CDD:291936	15/76 (20%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	297/638 (47%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	194/384 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850