Protein Alignment Hsc70-5 and hspa9

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001001229.1
• Gene: hspa9 / 407910
• XenbaseID: XB-GENE-960228
• Length: 670
• Species: Xenopus tropicalis
• Alignment Length: 678
• Identity: 502/678 - (74%)
• Similarity: 582/678 - (85%)
• Gaps: 20/678 - (2%)

  Fly    15 AGVVPSHMSGASSMFRNLPGASNGISSQL-------RYKSGEVKGAVIGIDLGTTNSCLAVMEGK 72
            :|.|.|.:|..|.:.|.  |..||:|..:       .|.|..:|||||||||||||||:|:||||
 Frog     5 SGSVASSLSHVSRILRK--GCFNGLSQDVLQSVFKRDYASESIKGAVIGIDLGTTNSCVAIMEGK 67

  Fly    73 QAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDIT 137
            ||||:||:||||||||.|||:.|.|||||||||||||||..|||||||||||||||||||:|||.
 Frog    68 QAKVLENSEGARTTPSVVAFSSDAERLVGMPAKRQAVTNPNNTFYATKRLIGRRFDDPEVQKDIK 132

  Fly   138 NLSYKVVKASNGDAWVSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQR 202
            |:.:|:|||||||||:.| .||:|||||||||:|||||||||.||....||||:|||||||||||
 Frog   133 NVPFKIVKASNGDAWLES-HGKLYSPSQIGAFVLMKMKETAENYLGHAAKNAVITVPAYFNDSQR 196

  Fly   203 QATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKST 267
            |||||||||:|||||||||||||||||||:||::|||||||||||||||||||||||||||||||
 Frog   197 QATKDAGQISGLNVLRVINEPTAAALAYGLDKSDDKIIAVYDLGGGTFDISILEIQKGVFEVKST 261

  Fly   268 NGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYL 332
            ||||.|||||||..::..:|.:||::||:|:.|||:|:||::||||||||||||:.|||||||||
 Frog   262 NGDTFLGGEDFDQALLQHIVKQFKRESGVDLTKDNMALQRVREAAEKAKCELSSALQTDINLPYL 326

  Fly   333 TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQS 397
            ||||:||:|:|:||||::.|.:|.||||||:.|.|||:.||||.||:|||||||||||||||||.
 Frog   327 TMDASGPKHLNMKLTRAQFEGIVADLIKRTVAPSQKAMQDAEVGKSDIGEVLLVGGMTRMPKVQQ 391

  Fly   398 TVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNT 462
            |||:||||.||::||||||||:|||:||||||||||||||||||||||||||||||||:||.|||
 Frog   392 TVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLIGRNT 456

  Fly   463 TIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDAN 527
            |||||||||||||:||||||||||||||||||:||||||.||||||||||||||||||.||||||
 Frog   457 TIPTKKSQVFSTAADGQTQVEIKVHQGEREMASDNKLLGQFTLVGIPPAPRGVPQIEVTFDIDAN 521

  Fly   528 GIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDT 592
            |||||||||||||:|||||||||||||||:||||:|.||:||..|::::|.:|.||..|.|:|||
 Frog   522 GIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRRKERVEAVNNAEGIIHDT 586

  Fly   593 ETKMEEFKSQLPAEECEKLKKEIADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSA 657
            |:||||||.||||:||.|||:||:.::.||..|:....|.:|.|:|:|||:||||||:|||||::
 Frog   587 ESKMEEFKDQLPADECNKLKEEISKVKELLTRKDEETGETIRNASSTLQQASLKLFEMAYKKMAS 651

  Fly   658 ERESNAGAGSSDSSSSSDTSGEAKKEEK 685
            ||          ||:.|....|.:||||
 Frog   652 ER----------SSTESGQQKEDQKEEK 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	482/614 (79%)
hspa9	NP_001001229.1	dnaK	46..664	CDD:234715	485/628 (77%)