Protein Alignment Hsc70-5 and Hsc70Cb

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 184/701 - (26%)
• Similarity: 319/701 - (45%)
• Gaps: 141/701 - (20%)

  Fly    53 AVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDG-ERLVGMPAKRQAVTNSANTF 116
            :|||||.|..:..:|.......:.:.|....|.|||.|||  || :|::|:.||.|.|||..||.
  Fly     2 SVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAF--DGKKRIIGVAAKNQQVTNMKNTV 64

  Fly   117 YATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSST---DGKVYSPSQIGAFILMKMKETA 178
            ...|||:||:|:||.|:.::|::..:|....:|...:...   :.:.:.|.|:.|.:..|:|||:
  Fly    65 GGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETS 129

  Fly   179 EAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGM---DKTEDK-- 238
            .|.:.|.|.:.|:..|.:|.:::|:|..||.|||||||||::||.||.|||||.   |..|||
  Fly   130 AAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPR 194

  Fly   239 -IIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDN 302
             :|.| |.|..:...|.....||..::.::..|. :||.|.|..:.::...||::...|:.:.:.
  Fly   195 NVIFV-DFGHSSLQASACAFTKGKLKMLASTWDQ-IGGRDIDLALGDYFAKEFQERYKINAKTNA 257

  Fly   303 IAMQRLKEAAEKAKCELS-SSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPC 366
            .|..||....||.|.::| :|.:..:|:.....|.    .::..:.||::|.|...:::|..|..
  Fly   258 RANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDI----DVSSSMQRSQMEELCAPVLQRVEQTF 318

  Fly   367 QKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAG- 430
            ::.|:::::...:|..|.:|||.:|:|.|:..::::|.:..|.::|.||||:.|||:|..:::.
  Fly   319 KRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPA 383

  Fly   431 ------DVTDVLLLDVTPL--SLGIETLGGV----------FTRLISRNTTIPTKKSQVFSTASD 477
                  .|||:....|..|  |.|....|.:          |:||::.|...|...|.|:
  Fly   384 VRVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVY----- 443

  Fly   478 GQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQ-IEVVFDIDANGIVHVSA------- 534
            ||            ::...::.:|.:.:..:.|..||..| :::...|:.||||.:|:
  Fly   444 GQ------------QVPYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKK 496

  Fly   535 ----------------------------------------------------------------- 534
                                                                             
  Fly   497 EAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFG 561

  Fly   535 ----KDKGTGKEQQIVIQ-SSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTET 594
                |.|...|..::.:: ::.|.|..::.|..::..:....|:::.|.|:..|..|..|:|...
  Fly   562 SGADKKKKASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRN 626

  Fly   595 KME--EFKSQLPAEECEKLKKEIADLRTLLANKETADLEEVRK--ATSSLQ 641
            |::  .|:..:...|.||:..::.||...|..    |.|:..:  .||.||
  Fly   627 KLQGGPFERYVVEAEREKIVSQLNDLENWLYE----DGEDCERDIYTSRLQ 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	184/701 (26%)
		HSPA9-like_NBD	51..428	CDD:212683	129/385 (34%)
		Syntaphilin	<566..>642	CDD:291936	21/80 (26%)
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	129/386 (33%)
		HSP70	3..682	CDD:278441	184/700 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830