Protein Alignment Hsc70-5 and Hsc70-1

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 304/633 - (48%)
• Similarity: 413/633 - (65%)
• Gaps: 19/633 - (3%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            :|||||||.||:.|.:..:.::|.|.:|.|||||:|||| :.|||:|..||.|...|..||.:..
  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-ESERLIGDAAKNQVAMNPNNTIFDA 70

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            ||||||||||..|:.|:.:..::|. |.||...:.   ..:.|.:.|.::.:.:|.||:||||||
  Fly    71 KRLIGRRFDDATVQSDMKHWPFEVF-AENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAY 134

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK--TEDKIIAVYD 244
            |...|.:|||||||||||||||||||||.||||||||:||||||||:|||:||  |.::.:.::|
  Fly   135 LGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFD 199

  Fly   245 LGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLK 309
            |||||||:|:|.|:.|:||||:|.|||.||||||||.:||..|.||::....|:.::..|::||:
  Fly   200 LGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLR 264

  Fly   310 EAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAE 374
            .|.|:||..||||.|..|.:..|....    .....:||::.|.|.|||.:.|::|..|||.||:
  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGV----DFYTSVTRARFEELNGDLFRGTMEPVAKALRDAK 325

  Fly   375 VSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD----VTD 434
            :.|.:|.:::||||.||:||||..:|:.| |::.::|:|||||||.|||||..:|.||    |.|
  Fly   326 MDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQD 390

  Fly   435 VLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKL 499
            :||||||||||||||.|||.|.||.||||||||::|:|:|.:|.|..|.|:|.:|||.|..||..
  Fly   391 LLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNS 455

  Fly   500 LGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIENMIK 563
            ||.|.|..||||||||||:||.||||||||::|:|.:|.||||.:|.| ...|.|||::||.|:.
  Fly   456 LGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVN 520

  Fly   564 KAEEYATADKQKRELIEIVNQGESIVHDTETKM--EEFKSQLPAEECEKLKKEIADLRTLLANKE 626
            .||.|..||:|:|:.|...||.||......:.:  |...|:....:.|.:::..::....|...:
  Fly   521 DAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQ 585

  Fly   627 TADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSS 674
            .|:.:|.......|::....:....|:.........||..:..::..|
  Fly   586 LAERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGS 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	303/623 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	194/378 (51%)
		Syntaphilin	<566..>642	CDD:291936	18/77 (23%)
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	304/633 (48%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	194/379 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850