Protein Alignment Hsc70-5 and hsc70

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 648
• Identity: 314/648 - (48%)
• Similarity: 423/648 - (65%)
• Gaps: 24/648 - (3%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..:|||||||.||:.:.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|.:||
Zfish     3 KGPAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPSNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDG--KVYSPSQIGAFILMKMKETA 178
            .:..|||||||||||.|:.|:.:..:||:...:.........|  |.:.|.::.:.:|.||||.:
Zfish    67 VFDAKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEIS 131

  Fly   179 EAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKIIA 241
            ||||...|.|||:||||||||||||||||||.||||||||:||||||||:|||:||.  .::.:.
Zfish   132 EAYLGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVL 196

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            ::||||||||:|||.|:.|:||||||.|||.||||||||.:||..:.|||:....||..:..|::
Zfish   197 IFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVR 261

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALS 371
            ||:.|.|:||..||||.|..|.:..|...|    .....:||::.|.|..||.:.|::|.:|||.
Zfish   262 RLRTACERAKRTLSSSTQASIEIDSLYEGA----DFYTSITRARFEELNADLFRGTLEPVEKALR 322

  Fly   372 DAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD---- 431
            ||::.|::|.:::||||.||:||:|..:|:.| ||..::|:|||||||.|||||..:|.||
Zfish   323 DAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSEN 387

  Fly   432 VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMAND 496
            |.|:||||||||||||||.|||.|.||.||||||||::|.|:|.||.|..|.|:|::|||.|..|
Zfish   388 VQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKD 452

  Fly   497 NKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIEN 560
            |.:||.|.|.||||||||||||||.||||||||::|||.||.||||.:|.| ...|.|||::||.
Zfish   453 NNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIER 517

  Fly   561 MIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQ--LPAEECEKLKKEIADLRTLLA 623
            |:::|::|...|:.:||.:...|..||:..:.::.:|:.|.|  :..|:.:.:..:..::.:.|.
Zfish   518 MVQEADQYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLD 582

  Fly   624 NKETADLEEVRKATSSLQQSSLKLFELAYK-------KMSAERESNAGAGSSDSSSSSDTSGE 679
            ..:||:.:|.......|::....:....|:       .|..........|....|||..|..|
Zfish   583 KNQTAEKDEYEHQQKELEKVCNPIITKLYQGAGGMPGGMPGGMPGGYPGGQGSGSSSGPTIEE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	308/633 (49%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	306/613 (50%)