Protein Alignment Hsc70-5 and hspa5

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_998223.1
• Gene: hspa5 / 378848
• ZFINID: ZDB-GENE-031001-11
• Length: 650
• Species: Danio rerio
• Alignment Length: 638
• Identity: 313/638 - (49%)
• Similarity: 425/638 - (66%)
• Gaps: 23/638 - (3%)

  Fly    49 EVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSA 113
            |..|.|||||||||.||:.|.:..:.::|.|.:|.|.|||:||||.:||||:|..||.|..:|..
Zfish    23 ESVGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPE 87

  Fly   114 NTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNG---DAWVSSTDGKVYSPSQIGAFILMKMK 175
            ||.:..||||||.:.|..|::||....:||::..|.   ...:.|...|.::|.:|.|.:|.|||
Zfish    88 NTVFDAKRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMK 152

  Fly   176 ETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DKI 239
            |||||||...|.:|||||||||||:|||||||||.||||||:|:||||||||:|||:||.: :|.
Zfish   153 ETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDGEKN 217

  Fly   240 IAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIA 304
            |.|:||||||||:|:|.|..|||||.:|||||.|||||||..::...:..:||.:|.|:||||.|
Zfish   218 ILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRA 282

  Fly   305 MQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKA 369
            :|:|:...||||..||:..|..|.:......    :..:..|||:|.|.|..||.:.|::|.||.
Zfish   283 VQKLRREVEKAKRALSAQHQARIEIESFFEG----EDFSETLTRAKFEELNMDLFRSTMKPVQKV 343

  Fly   370 LSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG--D 431
            |.|::..|.:|.|::||||.||:||:|..|:|.| |::|||.:|||||||.|||||.|||:|  :
Zfish   344 LEDSDPKKPDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEE 408

  Fly   432 VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMAND 496
            ..|::||||.||:|||||:|||.|:||.|||.:||||||:||||||.|..|.|||::|||.:..|
Zfish   409 TGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKD 473

  Fly   497 NKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIEN 560
            |.|||:|.|.||||||||||||||.|:||.|||:.|:|:|||||.:.:|.| .....|:.::||.
Zfish   474 NHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIER 538

  Fly   561 MIKKAEEYATADKQKRELIEIVNQGESIVHDTETKM---EEFKSQLPAEECEKLKKEIADLRTLL 622
            |:.:||.:|..||:.:|.|:..|:.||..:..:.::   |:...:|.:|:.|.::|.:.:....|
Zfish   539 MVNEAERFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWL 603

  Fly   623 ANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSD 675
            ...:.|||||.        |:..|..|...:.:.::...:||....:.:...|
Zfish   604 EAHQDADLEEF--------QAKKKELEEVVQPIVSKLYGSAGGPPPEEAEEKD 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	311/625 (50%)
		HSPA9-like_NBD	51..428	CDD:212683	201/381 (53%)
		Syntaphilin	<566..>642	CDD:291936	20/78 (26%)
hspa5	NP_998223.1	HSPA5-like_NBD	26..401	CDD:212681	200/378 (53%)
		PTZ00009	29..641	CDD:240227	309/623 (50%)
		Periplasmic_Binding_Protein_Type_2	<583..640	CDD:304360	15/64 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237853at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920