Protein Alignment Hsc70-5 and F11F1.1

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001255199.1
• Gene: F11F1.1 / 3565569
• WormBaseID: WBGene00008714
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 203/580 - (35%)
• Similarity: 341/580 - (58%)
• Gaps: 28/580 - (4%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            ||||||||.||:|..:..|..::||..|.|||||.:|..:||:.|:|..|| ..:..:.|:.:..
 Worm     3 IGIDLGTTFSCVAYYQNGQVNILENENGCRTTPSVLAVGEDGDLLIGQHAK-DVIGKATNSLFDV 66

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDGK---VYSPSQIGAFILMKMKETAEAY 181
            ||:||||:||..:::|:....:||.|..||..::.....:   .:|...:.:.||..:|..||..
 Worm    67 KRIIGRRYDDVLLQRDMPLWPFKVEKDDNGIPYLEIHKNEKPLKFSAVTVSSLILRCLKYNAERK 131

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGM--DKTEDKIIAVYD 244
            |...||:||:|||||||.:||:||::|.:||||.|||::|||||||:||.:  .:...:.|.:||
 Worm   132 LGLEVKSAVITVPAYFNATQRRATEEAAEIAGLKVLRILNEPTAAAIAYSLKGQRLSRRNILIYD 196

  Fly   245 LGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLK 309
            |||||||::.:.:......||:..|||.|||:|.||.|:..::.|||...|||::.:..|::|::
 Worm   197 LGGGTFDVAAVNVDGPRITVKAKGGDTHLGGQDIDNIIMIKMLEEFKNRHGIDLKGNYRALKRIR 261

  Fly   310 EAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMN----LKLTRSKLESLVGDLIKRTIQPCQKAL 370
            :|||.||..||:|....|.|..|        |:.    ::::|:..||.:.:|:..|:...::.:
 Worm   262 KAAEVAKITLSASSVARIELECL--------HLGIDFIMRISRTDFESWIENLLMATVIHVERVI 318

  Fly   371 SDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF--GRQPSRSVNPDEAVAVGAAVQGGVLAG--D 431
            .:|.:.||:|.|::||||.||:|.:::.:::.|  ..:...|::||||||.|||:...||:|  :
 Worm   319 REANLKKSQINEIVLVGGSTRIPILKNIIKQSFESNTRICESIHPDEAVAYGAAIMAAVLSGAEE 383

  Fly   432 VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMAND 496
            |.|:.|:||.|:|:|::......:.||.:.|..|..|.:.|..:.|.||.:.:.|::|||.:.:.
 Worm   384 VQDMRLIDVIPMSIGVQCNRDYMSVLIKKGTVFPCTKRKTFINSDDFQTSINVPVYEGERVLCSH 448

  Fly   497 NKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKE-QQIVIQSSGGLSKDEIEN 560
            |:.||..:| .|.|..||...:::..::|.|||:..:|.|..|.|. ...::......::.||:.
 Worm   449 NRQLGEISL-PIQPKRRGESVVDITLEVDYNGILQATALDLNTKKAITTTILYDCCTYTQPEIDE 512

  Fly   561 MIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLP----AEECEKLKKEIA 616
            |..::||....|:..:...:.:.:.|.:.:..:.::|:.|..:.    :...|.:::||:
 Worm   513 MTSQSEEDRIFDEHFKMRYKQLQKSEDMAYGYKHRLEKVKGSVEPGKFSNLMETVEREIS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	203/580 (35%)
		HSPA9-like_NBD	51..428	CDD:212683	151/383 (39%)
		Syntaphilin	<566..>642	CDD:291936	9/55 (16%)
F11F1.1	NP_001255199.1	HSP70	3..598	CDD:365808	203/580 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910