Protein Alignment Hsc70-5 and ssa2

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_588421.1
• Gene: ssa2 / 2539225
• PomBaseID: SPCC1739.13
• Length: 647
• Species: Schizosaccharomyces pombe
• Alignment Length: 658
• Identity: 308/658 - (46%)
• Similarity: 420/658 - (63%)
• Gaps: 46/658 - (6%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            ||||||||.||:......:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||.:..
pombe     5 IGIDLGTTYSCVGHFSNNRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPHNTIFDA 68

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDG------------KVYSPSQIGAFILM 172
            ||||||:||||||:.|:.:..:||:          |.||            |.::|.:|.:.:||
pombe    69 KRLIGRKFDDPEVQSDMKHWPFKVI----------SKDGKPVLQVEYKGETKTFTPEEISSMVLM 123

  Fly   173 KMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE- 236
            ||:|||||||...|.:|||||||||||||||||||||.||||||||:||||||||:|||:|::.
pombe   124 KMRETAEAYLGGKVTDAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDRSNQ 188

  Fly   237 -DKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRK 300
             :..:.::||||||||:|:|.|::|:||||:|.|||.|||||||:.:||..:.|||:.:..||..
pombe   189 GESNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDSRLVNHFIQEFKRKNKKDITG 253

  Fly   301 DNIAMQRLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTI 363
            :..|::||:.|.|:||..||||.|..|.:..|  .:|      ....:||::.|.|..||.::|:
pombe   254 NARAVRRLRTACERAKRTLSSSAQASIEIDSLFEGID------FYTSITRARFEELCADLFRKTM 312

  Fly   364 QPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGV 427
            :|.::.|.|::|.|:.:.|::||||.||:|:||..|.:.| |::|.:|:|||||||.|||||..|
pombe   313 EPVERVLRDSKVDKASVNEIVLVGGSTRIPRVQKLVSDFFNGKEPCKSINPDEAVAYGAAVQAAV 377

  Fly   428 LAGDVT----DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQ 488
            |.||.:    |:|||||.|||:||||.|||.|.||.||||||||||::|||.||.|..|.|:|.:
pombe   378 LTGDTSEKTQDLLLLDVAPLSMGIETAGGVMTPLIKRNTTIPTKKSEIFSTYSDNQPGVLIQVFE 442

  Fly   489 GEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGG 552
            |||....|..|||.|.|.||||||||||||||.||:|||||::|||.:|||||.|:|.| ...|.
pombe   443 GERARTKDCNLLGKFELSGIPPAPRGVPQIEVTFDVDANGILNVSALEKGTGKTQKITITNDKGR 507

  Fly   553 LSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEI 615
            |||:||:.|:.:||:|...|:.:...|:..|..||..:.....:::  .|.::.|.:.|.:.|.:
pombe   508 LSKEEIDRMVAEAEKYKAEDEAESGRIQAKNHLESYAYSLRNSLDDPNLKDKVDASDKETVDKAV 572

  Fly   616 ADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAE-----RESNAGAGSSDSSSSSD 675
            .:....|.:..||..:|.......|:..:..:....|:...|.     ....|..|::..::...
pombe   573 KETIEWLDSNTTAAKDEFEAKQKELESVANPIMAKIYQAGGAPGGMPGAAPGAAPGAAPGAAPGG 637

  Fly   676 TSGEAKKE 683
            .:|...:|
pombe   638 DNGPEVEE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	305/639 (48%)
		HSPA9-like_NBD	51..428	CDD:212683	195/389 (50%)
		Syntaphilin	<566..>642	CDD:291936	16/77 (21%)
ssa2	NP_588421.1	PTZ00009	4..647	CDD:240227	308/658 (47%)
		HSPA1-2_6-8-like_NBD	4..379	CDD:212675	196/390 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810