Protein Alignment Hsc70-5 and hsp-3

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 311/641 - (48%)
• Similarity: 432/641 - (67%)
• Gaps: 26/641 - (4%)

  Fly    52 GAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKD-GERLVGMPAKRQAVTNSANT 115
            |.:||||||||.||:.|.:..:.::|.|.:|.|.|||:|||:.| |:||:|..||.|...|..||
 Worm    33 GTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENT 97

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNG---DAWVSSTDGKVYSPSQIGAFILMKMKET 177
            .:..||||||.::|..|:.||.:..:||:..||.   :..|.| |.|.::|.::.|.:|:||||.
 Worm    98 IFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGS-DNKQFTPEEVSAMVLVKMKEI 161

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DKIIA 241
            ||:||...||||||||||||||:|||||||||.||||||:|:||||||||:|||:||.: ::.|.
 Worm   162 AESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNIL 226

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            |:||||||||:|:|.|..|||||.:|||||.|||||||..::.:.:..:||.||.|:|||..|:|
 Worm   227 VFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQ 291

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALS 371
            :|:...||||..||:..||.:.:..| .|.   :..:..|||:|.|.|..||.:.|::|.||.|.
 Worm   292 KLRREVEKAKRALSTQHQTKVEIESL-FDG---EDFSETLTRAKFEELNMDLFRATLKPVQKVLE 352

  Fly   372 DAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG--DVT 433
            |:::.|.::.|::||||.||:||||..::|.| |::|||.:|||||||.||||||||::|  |..
 Worm   353 DSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTG 417

  Fly   434 DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNK 498
            :::||||.||::||||:|||.|:||.|||.||||||||||||:|.|..|.|:|.:|||.|..||.
 Worm   418 EIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNH 482

  Fly   499 LLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIENMI 562
            .||.|.|.|:||||||||||||.|:||.|||:||:|:|||||.:.:|.| .....||.::||.||
 Worm   483 QLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMI 547

  Fly   563 KKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE---FKSQLPAEECEKLKKEIADLRTLLAN 624
            ..||::|..||:.::..|..|:.||..::.:.::|:   ...:|..::.:.:::.:.:..:.|.:
 Worm   548 NDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGS 612

  Fly   625 KETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDS-SSSSDTSGE 679
            ...|..||:::....|:.....:....||        :||||..:: ...||...|
 Worm   613 NAEASAEELKEQKKDLESKVQPIVSKLYK--------DAGAGGEEAPEEGSDDKDE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	306/625 (49%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	308/627 (49%)