Protein Alignment Hsc70-5 and hsp-3

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 311/641 - (48%)
• Similarity: 432/641 - (67%)
• Gaps: 26/641 - (4%)

  Fly    52 GAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKD-GERLVGMPAKRQAVTNSANT 115
            |.:||||||||.||:.|.:..:.::|.|.:|.|.|||:|||:.| |:||:|..||.|...|..||
 Worm    33 GTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENT 97

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNG---DAWVSSTDGKVYSPSQIGAFILMKMKET 177
            .:..||||||.::|..|:.||.:..:||:..||.   :..|.| |.|.::|.::.|.:|:||||.
 Worm    98 IFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGS-DNKQFTPEEVSAMVLVKMKEI 161

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DKIIA 241
            ||:||...||||||||||||||:|||||||||.||||||:|:||||||||:|||:||.: ::.|.
 Worm   162 AESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNIL 226

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            |:||||||||:|:|.|..|||||.:|||||.|||||||..::.:.:..:||.||.|:|||..|:|
 Worm   227 VFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQ 291

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALS 371
            :|:...||||..||:..||.:.:..| .|.   :..:..|||:|.|.|..||.:.|::|.||.|.
 Worm   292 KLRREVEKAKRALSTQHQTKVEIESL-FDG---EDFSETLTRAKFEELNMDLFRATLKPVQKVLE 352

  Fly   372 DAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG--DVT 433
            |:::.|.::.|::||||.||:||||..::|.| |::|||.:|||||||.||||||||::|  |..
 Worm   353 DSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTG 417

  Fly   434 DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNK 498
            :::||||.||::||||:|||.|:||.|||.||||||||||||:|.|..|.|:|.:|||.|..||.
 Worm   418 EIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNH 482

  Fly   499 LLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIENMI 562
            .||.|.|.|:||||||||||||.|:||.|||:||:|:|||||.:.:|.| .....||.::||.||
 Worm   483 QLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMI 547

  Fly   563 KKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE---FKSQLPAEECEKLKKEIADLRTLLAN 624
            ..||::|..||:.::..|..|:.||..::.:.::|:   ...:|..::.:.:::.:.:..:.|.:
 Worm   548 NDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGS 612

  Fly   625 KETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDS-SSSSDTSGE 679
            ...|..||:::....|:.....:....||        :||||..:: ...||...|
 Worm   613 NAEASAEELKEQKKDLESKVQPIVSKLYK--------DAGAGGEEAPEEGSDDKDE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	306/625 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	202/381 (53%)
		Syntaphilin	<566..>642	CDD:291936	15/78 (19%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	308/627 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237853at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820