Protein Alignment Hsc70-5 and hsp-110

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_498868.1
• Gene: hsp-110 / 176195
• WormBaseID: WBGene00016250
• Length: 776
• Species: Caenorhabditis elegans
• Alignment Length: 639
• Identity: 179/639 - (28%)
• Similarity: 293/639 - (45%)
• Gaps: 84/639 - (13%)

  Fly    53 AVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAF-TKDGERLVGMPAKRQAVTNSANTF 116
            :|:|.|:|..|..:.|......:||.|......||:.|:| .||  |.:|:.|::...||..||.
 Worm     2 SVLGFDIGNLNCYIGVARQGGIEVITNDYSLHATPACVSFGPKD--RSMGVAARQAVTTNIKNTV 64

  Fly   117 YATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSST---DGKVYSPSQIGAFILMKMKETA 178
            ...|.||||:|.||..::.|..:..||||..|.|..|..:   :...::|.|:.|.:|.|::...
 Worm    65 INFKHLIGRKFSDPVAQRFIPFIPCKVVKLPNDDIGVQVSYLGEPHTFTPEQVLAALLTKLRTIV 129

  Fly   179 EAYLN--TPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK------- 234
            |:.|:  ..|.:.|:.||:||.|.||:|...|.|.||||.||::||.||.|||||:.|
 Worm   130 ESQLSDVKKVSDCVLAVPSYFTDVQRRAVLSAIQYAGLNSLRIVNETTAIALAYGIYKQDLPEED 194

  Fly   235 TEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIR 299
            .:.:.:...|:|..:...|::...:|..::.:|:.|...||..||..|......|||...|||..
 Worm   195 AKSRNVVFLDIGHSSTQASLVAFNRGKLQMVNTSYDLESGGIWFDALIREHFRKEFKTKYGIDAA 259

  Fly   300 KDNIAMQRLKEAAEKAKCELSSSQ-QTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTI 363
            .......||.:..|:.|.::|::| ...:|:.....|    :.:..|:.|.:.|.|...:..|..
 Worm   260 TSPRPWLRLLDECERVKKQMSANQTPIPLNIECFMED----KDVTGKMQRQEFEDLAAPIFNRIK 320

  Fly   364 QPCQKALSD-AEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGV 427
            |......:| ..:...||.|:.:|||.:|:|.::..|::|||::|..::|.|||||.|||:|..:
 Worm   321 QVLINLFADGVSIKPEEIDEIEIVGGSSRIPMIREIVKDLFGKEPKTTMNQDEAVARGAAMQCAI 385

  Fly   428 LAGD--VTDVLLLDVTP--LSLGIETLG--GVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKV 486
            |:..  |.:..:.|..|  :.|...:.|  |....:.|....:|.  |::.|....|...||  .
 Worm   386 LSPTFRVREFAIKDTQPYRIRLSWNSTGENGGENDVFSPRDEVPF--SKLVSLLRSGPFNVE--A 446

  Fly   487 HQGEREMANDNKL-LGSFTLVGI-PPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQS 549
            |..:..:...|:: :||:.:.|. |.|..|..:::|...::.:||..:::   .|..|.:||
 Worm   447 HYAQPNVVPHNQVHIGSWKVNGARPGADGGNQKVKVKVRVNPDGIFTIAS---ATMYEPRIV--- 505

  Fly   550 SGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKE 614
                                  ::...|.:|:  .|::            |::.|||..|.:||
 Worm   506 ----------------------EEVPAEAMEV--DGDA------------KTEAPAEPLEPVKK- 533

  Fly   615 IADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSS 668
                 |.|.   ..|||.:.....|.........||..::..|..::.|.|.:|
 Worm   534 -----TKLV---PVDLEVIESIPVSYDVQKFHNLELQMQESDAREKAKADAKNS 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	177/635 (28%)
		HSPA9-like_NBD	51..428	CDD:212683	128/389 (33%)
		Syntaphilin	<566..>642	CDD:291936	16/75 (21%)
hsp-110	NP_498868.1	HSPA4_like_NDB	2..387	CDD:212670	128/390 (33%)
		HSP70	3..650	CDD:278441	179/638 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900