Protein Alignment Hsc70-5 and hsp-4

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 309/643 - (48%)
• Similarity: 429/643 - (66%)
• Gaps: 25/643 - (3%)

  Fly    49 EVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKD-GERLVGMPAKRQAVTNS 112
            |..|.:||||||||.||:.|.:..:.::|.|.:|.|.|||:|||:.| ||||:|..||.|...|.
 Worm    27 EKMGTIIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINP 91

  Fly   113 ANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNG---DAWVSSTDGKVYSPSQIGAFILMKM 174
            .||.:..||||||.:::..|::||.:..:|:|..||.   :..|.| :.|.::|.::.|.:|.||
 Worm    92 ENTIFDAKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGS-ETKQFTPEEVSAMVLTKM 155

  Fly   175 KETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DK 238
            |:.||:||...||||||||||||||:|:|||||||.||||||:|:||||||||:|||:||.: ::
 Worm   156 KQIAESYLGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKKDGER 220

  Fly   239 IIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNI 303
            .|.|:||||||||:|:|.|..|||||.:|||||.|||||||..::.:.:..:||.||.|:||||.
 Worm   221 NILVFDLGGGTFDVSLLTIDSGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDNR 285

  Fly   304 AMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            |:|:|:...||||..||:..||.|.:..| .|.   :..:..|||:|.|.|..||.:.|::|.||
 Worm   286 AVQKLRREVEKAKRALSTQHQTKIEIESL-FDG---EDFSETLTRAKFEELNMDLFRATLKPVQK 346

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG-- 430
            .|.||::.|:::.|::||||.||:||||..:::.| |::|||.:|||||||.|||||.||:.|
 Worm   347 VLEDADMKKTDVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGGVE 411

  Fly   431 DVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMAN 495
            :..||:||||.||:|||||:|||.|:||.|||.||||||||||||:|.|:.|.|.:::|||.|..
 Worm   412 NTGDVVLLDVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVM 476

  Fly   496 DNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSS-GGLSKDEIE 559
            ||..||:|.:.||||||||||||||.|:||.|||:||||:|||||.:.::.|.:. ..||.::||
 Worm   477 DNHKLGNFDVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIE 541

  Fly   560 NMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKM---EEFKSQLPAEECEKLKKEIADLRTL 621
            .||..|:::|..|:.::|.:|..|:.|:..:..:|::   |:...:|..|:...::..:......
 Worm   542 RMINDADKFAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEW 606

  Fly   622 LANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGE 679
            |.:.:.|..||.::....|:.....:....|        |..|.|...|...|:...|
 Worm   607 LGSNQDASTEENKEQKKELESVVQPIVSKLY--------SAGGQGEQASEEPSEDHDE 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	304/626 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	200/382 (52%)
		Syntaphilin	<566..>642	CDD:291936	15/78 (19%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	303/622 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237853at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820