Protein Alignment Hsc70-5 and hsp-70

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 309/649 - (47%)
• Similarity: 421/649 - (64%)
• Gaps: 34/649 - (5%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            ||||||||.||:.:.:..:.:::.|:||.:||||:|||| |.|||||..||.||..|..||.:..
 Worm     7 IGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFT-DTERLVGDAAKDQAARNPENTVFDA 70

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            |||||||||:..|:.||.:..: .||...|...|.   ..:.:.::..:|.|.:|.||||||||.
 Worm    71 KRLIGRRFDEETVQSDIKHWPF-TVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAV 134

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK--TEDKIIAVYD 244
            |...|::||:|||||||||||||||||..|||||.:|:||||||||||||:||  |::|.|.::|
 Worm   135 LGHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDEKNILIFD 199

  Fly   245 LGGGTFDISILEIQKG-VFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRL 308
            |||||||:|||.|.:| :||||||.|||.|||||||:.::...:.|||:.:|.||..:..|::||
 Worm   200 LGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRAIRRL 264

  Fly   309 KEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDA 373
            :.|.|:||..||||.:..:.:..| .|..   ....|:||::.|.|..||.::|::|.:|||.||
 Worm   265 RTACERAKRTLSSSTEATVEVDSL-FDGT---DFYSKITRARFEELCADLFRKTLEPVEKALRDA 325

  Fly   374 EVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAG----DVT 433
            :..|..|.||:||||.||:||:|..::|.| |:..:.|:|||||||.|||||..||:|    .:.
 Worm   326 KTDKGRIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLSGVKDDTIK 390

  Fly   434 DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNK 498
            ||||:||.|||.||||.|||.|.||.|||.||.|.|:.|:|.:|.|..|.|:|::|||.|..||.
 Worm   391 DVLLVDVVPLSHGIETAGGVMTNLIDRNTRIPAKASKTFTTYADNQPGVSIQVYEGERAMTRDNH 455

  Fly   499 LLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQS-SGGLSKDEIENMI 562
            .||:|.|.|||||||||||::|.||||||||::|||.||.||:..:|.|:: .|.||:.:|:.|:
 Worm   456 RLGTFELTGIPPAPRGVPQVDVTFDIDANGILNVSAADKSTGRSNRITIRNEKGRLSQADIDRMV 520

  Fly   563 KKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADL-----RTLL 622
            .:|:::...|..:|:.|...||.|:.....:..:||..|.|.||:.::.|..:.|.     |..|
 Worm   521 NEAKQFEREDAAQRDRISSRNQLEAYAFQVKQALEEHGSLLSAEDAKRAKDAVEDTLRWMERNTL 585

  Fly   623 ANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSS---SSSDTSGEAKKE 683
            |:|:  ::|...|...|:.|      ::..|....|.:|.:|.|:..|.   ||:...|...:|
 Worm   586 ADKD--EIEAKDKELKSICQ------DILTKMHQQEAQSGSGCGNPGSGGFHSSNYPQGPTVEE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	303/627 (48%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	309/649 (48%)