Protein Alignment Hsc70-5 and LOC1275756

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_315042.3
• Gene: LOC1275756 / 1275756
• VectorBaseID: AGAMI1_000862
• Length: 647
• Species: Anopheles gambiae
• Alignment Length: 664
• Identity: 312/664 - (46%)
• Similarity: 416/664 - (62%)
• Gaps: 64/664 - (9%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            |...:|||||||.||:.|.:..:..:|.|.:|.|||||:|||| |.|||:|..||.|...|..||
Mosquito     3 KTPAVGIDLGTTYSCVGVFQHGKVDIIANDQGNRTTPSYVAFT-DSERLIGDAAKNQVAMNPNNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDG-------------KVYSPSQIG 167
            .:..||||||:|||..|:.|:.:..:.|:           :||             |.:.|.::.
Mosquito    67 IFDAKRLIGRKFDDATVQADMKHWPFDVI-----------SDGGKPKLQVEYKGEKKSFFPEEVS 120

  Fly   168 AFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGM 232
            :.:|.||||||||||...:.|||:||||||||||||||||||.||||||||:||||||||:|||:
Mosquito   121 SMVLTKMKETAEAYLGKSIANAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 185

  Fly   233 DK--TEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSG 295
            ||  ..::.:.::||||||||:|||.|:.|:||||||.|||.||||||||.:|:..|.|||:...
Mosquito   186 DKKGAGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHFVEEFKRKHK 250

  Fly   296 IDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLP--YLTMDAAGPQHMNLKLTRSKLESLVGDL 358
            .||..:..|::||:.|.|:||..||:|.|..|.:.  |..:|      ....:||::.|.|..||
Mosquito   251 KDITSNKRALRRLRTACERAKRTLSASTQASIEIDSLYEGID------FYTSITRARFEELNSDL 309

  Fly   359 IKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAA 422
            .:.|::|..|||.||::.|:.|.:::||||.||:||||..:|:.| |::.::|:|||||||.|||
Mosquito   310 FRDTMEPVSKALRDAKMDKASIHDIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAA 374

  Fly   423 VQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVE 483
            ||..:|.||    |.|:||||||||||||||.|||.|.||.||||||||::|.|:|.||.|..|.
Mosquito   375 VQAAILQGDTSEAVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVL 439

  Fly   484 IKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI- 547
            |:|.:|||.|..||.|||.|.|.||||||||||||||.||||||||::|||.:|.|.||.:|.|
Mosquito   440 IQVFEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGIMNVSAIEKSTNKENRITIT 504

  Fly   548 QSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLK 612
            ...|.|||::|:.|:.:||::...|:::||.|...|..|:...:.::.||:          ..:|
Mosquito   505 NDKGRLSKEDIDRMVNEAEKFRNEDEKQREKISAKNSLEAYCFNMKSTMED----------ANIK 559

  Fly   613 KEIADL-RTLLANK-----------ETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESN-AG 664
            .:|.|. :||:.:|           :||:.||.......|:.....:.:..|:......... .|
Mosquito   560 DKIPDADKTLIMDKCNATIAWLDGNQTAEKEEFEHKQKELEAVCNPIIQKLYQGAGGMPGGGMPG 624

  Fly   665 AGSSDSSSSSDTSG 678
            .|...:..:..|||
Mosquito   625 GGMPGAGGAPPTSG 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	308/650 (47%)
LOC1275756	XP_315042.3	PTZ00009	1..647	CDD:240227	312/664 (47%)