Protein Alignment Hsc70-5 and hspa2

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_004917261.1
• Gene: hspa2 / 100496396
• XenbaseID: XB-GENE-992125
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 623
• Identity: 314/623 - (50%)
• Similarity: 410/623 - (65%)
• Gaps: 38/623 - (6%)

  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119
            :|||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|.|||.:..
 Frog     8 VGIDLGTTYSCVGVFQHGKVEIIANEQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPANTIFDA 71

  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181
            |||||||||||.|:.|:.:..:.|| :..|...|.   ..:.|.:.|.:|.:.:|.||||.||||
 Frog    72 KRLIGRRFDDPTVQADMKHWPFTVV-SDGGKPKVKVEFKGENKTFFPEEISSMVLSKMKEVAEAY 135

  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT-----EDKIIA 241
            |...|.|||:||||||||||||||||||.|:|:||||:||||||||:|||:||.     |..::
 Frog   136 LGVKVPNAVITVPAYFNDSQRQATKDAGVISGINVLRIINEPTAAAIAYGLDKKGAGHGETNVL- 199

  Fly   242 VYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQ 306
            ::||||||||:|:|.|..|:||||||.|||.||||||||.:|...|.|||:.:..||..:..|::
 Frog   200 IFDLGGGTFDVSVLTIDGGIFEVKSTAGDTHLGGEDFDNRMVAHFVEEFKRKNKKDISGNKRAVR 264

  Fly   307 RLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALS 371
            ||:.|.|:||..||||.|..:.:..|...|    .....:||::.|.|..||.:.|::|.:|||.
 Frog   265 RLRTACERAKRTLSSSTQASLEIDSLYEGA----DFYTAITRARFEELCADLFRGTLEPVEKALR 325

  Fly   372 DAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD---- 431
            ||::.|::|.|::||||.||:||||..:|:.| ||:.::|:|||||||.|||||..:|:||
 Frog   326 DAKLDKAQIREIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDKSHN 390

  Fly   432 VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMAND 496
            |.|:|||||.||||||||.|||.|.||.||||||:|::|.|:|.||.|:.|.::|::|||.|..|
 Frog   391 VQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPSKQTQTFTTYSDNQSSVLVQVYEGERAMTRD 455

  Fly   497 NKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIEN 560
            |.|||.|.|.||||||||||||||.||||||||::|:|.||.||||.:|.| ...|.|||::||.
 Frog   456 NNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKEDIER 520

  Fly   561 MIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLANK 625
            |:..||:|...|:..|:.:...|..||..:..:...|:.|  |..:..||.|.:|.|     ..|
 Frog   521 MVNDAEKYKAEDELNRDRVAAKNGLESYAYHIKQTAEDEK--LKGKLSEKEKSQILD-----KCK 578

  Fly   626 ETAD-LEEVRKATSSLQQSSLKLFELAYKKMSAERESN 662
            |..| ||:.:.|...         |..:|:...|:..|
 Frog   579 EVIDWLEKNQMAEKD---------EFEHKQKELEKVCN 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	314/623 (50%)
hspa2	XP_004917261.1	PTZ00009	2..633	CDD:240227	314/623 (50%)