Protein Alignment Hsc70-5 and hspa8

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_002937574.2
• Gene: hspa8 / 100496320
• XenbaseID: XB-GENE-955426
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 321/652 - (49%)
• Similarity: 433/652 - (66%)
• Gaps: 29/652 - (4%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..:|||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
 Frog     3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKET 177
            .:..||||||||:|..|:.|:.:..:.|: :.:|...|.   ..:.|.:.|.:|.:.:|:||||.
 Frog    67 VFDAKRLIGRRFEDAVVQSDMKHWPFNVI-SDSGRPKVQVEYKAETKSFYPEEISSMVLVKMKEI 130

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKII 240
            |||||...|.|||:||||||||||||||||||.|:||||||:||||||||:|||:||.  .::.:
 Frog   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNV 195

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            .::||||||||:|||.|:.|:||||||.|||.||||||||.:||..|||||:....||..:..|:
 Frog   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFVAEFKRKHKKDIIDNKRAV 260

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLP--YLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            :||:.|.|:||..||||.|..|.:.  |..:|      ....:||::.|.|..||.:.|:.|.:|
 Frog   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGTLDPVEK 319

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD- 431
            ||.||::.||:|.:::||||.||:||:|..:|:.| |::.::|:|||||||.|||||..:|:||
 Frog   320 ALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDK 384

  Fly   432 ---VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREM 493
               |.|:||||||||||||||.|||.|.||.||||||||::|.|:|.||.|..|.|:|::|||.|
 Frog   385 SENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAM 449

  Fly   494 ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDE 557
            ..||.|||.|.|.||||||||||||||.||||||||::|||.||.||||.:|.| ...|.|||::
 Frog   450 TKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKED 514

  Fly   558 IENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIADLRT 620
            ||.|:::||:|...|:::|:.:...|..||...:.:..:|:  .|.::..|:.:|:..:..::.:
 Frog   515 IERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLKGKISDEDKQKILDKCNEVIS 579

  Fly   621 LLANKETADLEEVRKATSSLQQSS----LKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGEAK 681
            .|...:||:.||.......|::..    .||::.|............|||.:.|..:|  ||...
 Frog   580 WLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGAGGAPSGGAS--SGPTI 642

  Fly   682 KE 683
            :|
 Frog   643 EE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	314/633 (50%)
		HSPA9-like_NBD	51..428	CDD:212683	199/384 (52%)
		Syntaphilin	<566..>642	CDD:291936	17/77 (22%)
hspa8	XP_002937574.2	PTZ00009	1..613	CDD:240227	312/617 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920