Protein Alignment Hsc70-5 and hspa1a

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_012823021.1
• Gene: hspa1a / 100488052
• XenbaseID: XB-GENE-5842877
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 319/652 - (48%)
• Similarity: 424/652 - (65%)
• Gaps: 31/652 - (4%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..:|||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
 Frog     3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNT 66

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKET 177
            .:..|||||||||||.|:.|:.:..:.|:. ..|...|.   ..:.|.:...::.:.:|.||||.
 Frog    67 VFDAKRLIGRRFDDPVVQSDMKHWPFTVIN-DGGRPKVQVEYKGEAKTFYAEEVSSMVLTKMKEI 130

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKII 240
            :||||...:.|||:||||||||||||||||||.|:||||||:||||||||:|||:||.  .::.:
 Frog   131 SEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGGERNV 195

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            .::||||||||:|||.|:.|:||||||.|||.||||||||.:||..|.|||:....||.::..|:
 Frog   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFVGEFKRKHKKDITENKRAI 260

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLP--YLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            :||:.|.|:||..||||.|..|.:.  |..:|      ....|||::.|.|..||.:.|::|.:|
 Frog   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGID------FYTSLTRARFEELNADLFRGTLEPVEK 319

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD- 431
            ||.||::.|::|.:::||||.||:||:|..:|:.| ||:.::|:|||||||.|||||..:|:||
 Frog   320 ALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDK 384

  Fly   432 ---VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREM 493
               |.|:||||||||||||||.|||.|.||.||||||||::|.|:|.||.|..|.|:|.:|||.|
 Frog   385 SENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAM 449

  Fly   494 ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDE 557
            ..||.|||.|.|.||||||||||||||.||||||||::|||.||.||||.:|.| ...|.|||:|
 Frog   450 TKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEE 514

  Fly   558 IENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIADLRT 620
            ||.|:::|:.|...|:.:||.|...|..||:..:.::.:|:  .|.::..|:.:|:..:..::.:
 Frog   515 IERMVQEADRYKAEDEVQREKISAKNSLESLAFNMKSTVEDEKLKDKISPEDKQKILDKCNEVIS 579

  Fly   621 LLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERE--------SNAGAGSSDSSSSSDTS 677
            .|...:.|:.||.......||.....:....|:.......        ..||||:....||..|.
 Frog   580 WLDRNQMAEKEEYEHQQKELQNLCNPIITKLYQGAGGAGMPGGMPGGFPGAGAGAGGGGSSGPTI 644

  Fly   678 GE 679
            .|
 Frog   645 EE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	313/637 (49%)
hspa1a	XP_012823021.1	PTZ00009	1..612	CDD:240227	310/616 (50%)