Protein Alignment Hsc70-5 and hsp70.1

DIOPT Version :10

• Sequence 1: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001349288.1
• Gene: hsp70.1 / 100126123
• ZFINID: ZDB-GENE-990415-91
• Length: 643
• Species: Danio rerio
• Alignment Length: 646
• Identity: 324/646 - (50%)
• Similarity: 430/646 - (66%)
• Gaps: 26/646 - (4%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..||||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
Zfish     5 KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNT 68

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGD----AWVSSTDGKVYSPSQIGAFILMKMKE 176
            .:..|||||||||||.|:.|:.:.|:|||  |:|.    |.....:.|.::|.:|.:.:|:||||
Zfish    69 VFDAKRLIGRRFDDPVVQSDMKHWSFKVV--SDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKE 131

  Fly   177 TAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMD--KTEDKI 239
            .|||||...|.|||:||||||||||||||||||.||||||||:||||||||:|||:|  |:.::.
Zfish   132 IAEAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERN 196

  Fly   240 IAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIA 304
            :.::||||||||:|||.|:.|:||||:|.|||.||||||||.:||..|.|||:....||.::..|
Zfish   197 VLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRA 261

  Fly   305 MQRLKEAAEKAKCELSSSQQTDINLP--YLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQ 367
            ::||:.|.|:||..||||.|..|.:.  |..:|      ....:||::.|.|..||.:.|:.|.:
Zfish   262 LRRLRTACERAKRTLSSSSQASIEIDSLYEGID------FYTSITRARFEELCSDLFRGTLDPVE 320

  Fly   368 KALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD 431
            |||.||::.|::|.:::||||.||:||:|..:|:.| ||:.::|:|||||||.|||||..:|.||
Zfish   321 KALKDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGD 385

  Fly   432 ----VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGERE 492
                |.|:|||||.||||||||.|||.|.||.||||||||::|.|:|.||.|..|.|:|.:|||.
Zfish   386 TSGNVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERA 450

  Fly   493 MANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKD 556
            |..||.|||.|.|.||||||||||||||.||||||||::|||.||.|||:.:|.| ...|.|||:
Zfish   451 MTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKE 515

  Fly   557 EIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIADLR 619
            |||.|:::|::|...|..:||.|...|..||...:.:..:|:  .|.::..|:.:::.::..:..
Zfish   516 EIERMVQEADKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAV 580

  Fly   620 TLLANKETADLEEVRKATSSLQQSSLKLFELAYK-KMSAERESNAGAGSSDSSSSSDTSGE 679
            :.|.|.:.||.||.......|::....:....|: .|.|........|:|.:|:...|..|
Zfish   581 SWLENNQLADKEEYEHQLKELEKVCNPVISKLYQGGMPAGGCGAQARGASGASAQGPTIEE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	319/631 (51%)
hsp70.1	NP_001349288.1	PTZ00009	5..643	CDD:240227	324/646 (50%)