Protein Alignment Hsc70-5 and hsp70

DIOPT Version :9

• Sequence 1: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001106370.1
• Gene: hsp70 / 100037899
• XenbaseID: XB-GENE-485626
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 651
• Identity: 318/651 - (48%)
• Similarity: 428/651 - (65%)
• Gaps: 35/651 - (5%)

  Fly    51 KGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANT 115
            ||..:|||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|..||.|...|..||
 Frog     4 KGVAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPQNT 67

  Fly   116 FYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKET 177
            .:..||||||:|:||.|:.|:.:..::|| :.:|...|.   ..:.|.:.|.:|.:.:|:|||||
 Frog    68 VFDAKRLIGRKFNDPVVQSDLKHWPFQVV-SDHGKPKVKVEFKGEEKTFFPEEISSMVLIKMKET 131

  Fly   178 AEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK--TEDKII 240
            |||||...|.|||:||||||||||||||||||.||||||||:||||||||:|||:||  ..::.:
 Frog   132 AEAYLGHAVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGTRGERNV 196

  Fly   241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAM 305
            .::||||||||:|||.|..|:||||:|.|||.||||||||.:||..:.|||:....||.::..|:
 Frog   197 LIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFMEEFKRKHKKDISQNKRAL 261

  Fly   306 QRLKEAAEKAKCELSSSQQTDINLPYL--TMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQK 368
            :||:.|.|:||..||||.|..|.:..|  .:|      ....:||::.|.|..||.:.|::|.:|
 Frog   262 RRLRTACERAKRTLSSSSQASIEIDSLFEGID------FYTSITRARFEELCSDLFRGTLEPVEK 320

  Fly   369 ALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD- 431
            ||.||::.||:|.|::||||.||:||||..:|:.| ||:.::|:|||||||.|||||..:|.||
 Frog   321 ALRDAKLDKSQIDEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDK 385

  Fly   432 ---VTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREM 493
               |.|:|||||.|||||:||.|||.|.||.||||||||::|.|:|.||.|..|.|:|.:|||.|
 Frog   386 SENVQDLLLLDVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAM 450

  Fly   494 ANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDE 557
            ..||.|||.|.|.||||||||||||||.||||||||::|||.:|.:||:.:|.| ...|.|||::
 Frog   451 TKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKED 515

  Fly   558 IENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEE--FKSQLPAEECEKLKKEIADLRT 620
            ||.|:::||.|...|..:||.|:..|..||...:.::.:|:  .|.::...:...:.::...:.:
 Frog   516 IEKMVQEAERYKADDDAQREKIDAKNSLESYAFNLKSMVEDENMKGKISEGDKRIISEKCTQIIS 580

  Fly   621 LLANKETADLEEVRKATSSLQQSSLK------LFELAYKKMSAERE-SNAGAGSSDSSSSSDTSG 678
            .|.|.:.|:.:|.     :.||..|:      :.:|....|..... |:.||.:....||..|..
 Frog   581 WLENNQLAEKDEY-----AFQQKELERVCQPIITKLYQGSMPGSMPGSSCGAQARQGGSSGPTIE 640

  Fly   679 E 679
            |
 Frog   641 E 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	313/636 (49%)
		HSPA9-like_NBD	51..428	CDD:212683	202/384 (53%)
		Syntaphilin	<566..>642	CDD:291936	15/77 (19%)
hsp70	NP_001106370.1	PTZ00009	2..643	CDD:240227	318/651 (49%)
		HSPA1-2_6-8-like_NBD	7..382	CDD:212675	200/382 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010