| Sequence 1: | NP_523740.3 | Gene: | Mdr50 / 36582 | FlyBaseID: | FBgn0010241 | Length: | 1313 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_113948.1 | Gene: | Abcb11 / 83569 | RGDID: | 619930 | Length: | 1321 | Species: | Rattus norvegicus |
| Alignment Length: | 1319 | Identity: | 524/1319 - (39%) |
|---|---|---|---|
| Similarity: | 784/1319 - (59%) | Gaps: | 69/1319 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 43 KSKKKSKHD----ESDASDEED-GSQYHEDVKQ----VSYFQLFRYATKKDRALYVIGLLSAVAT 98
Fly 99 GLTTPANSLIFG---------NLANDMIDLGG-------LLESGKSYRADDAISTL--LLD---K 142
Fly 143 VRQFSLQNTYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRM 207
Fly 208 NEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLA 272
Fly 273 KKEVTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFF 337
Fly 338 IYASYALAFWYGVGLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACA 402
Fly 403 KVFHIIEQIPEINPIDGEGKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGP 467
Fly 468 SGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGRE 532
Fly 533 DATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEAT 597
Fly 598 SALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYF 662
Fly 663 NLVTTQ------------LGED--DGSVLSPT---GDIYKN---FDIKDEDEEEIKVLSEDEDED 707
Fly 708 VMVTDEKNKKKKKKK---VKDPNEVKPMLEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGS 769
Fly 770 ILQILSVKDNDQYVRENSNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQ 834
Fly 835 EVAWFDDKANGTGSLCARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAF 899
Fly 900 TPFILIAFYMQRTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVE 964
Fly 965 ISKRNTHFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQALIMGTASIANALAF 1029
Fly 1030 APNMQKGVSAAKTIFTFLRRQP--SIVDRPGVSRDPWHS-EGYVRFDKVKFSYPTRSEIQVLKGL 1091
Fly 1092 ELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGIVSQEPI 1156
Fly 1157 LFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQLSGGQKQRIAI 1221
Fly 1222 ARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIAHRLSTVVHSDVIFVFENGLV 1286
Fly 1287 CEAGDHKQLLANRGLYYTL 1305 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr50 | NP_523740.3 | PTZ00265 | 69..1308 | CDD:240339 | 515/1288 (40%) |
| ABC_membrane | 92..382 | CDD:279056 | 89/310 (29%) | ||
| ABC_MTABC3_MDL1_MDL2 | 431..668 | CDD:213216 | 145/236 (61%) | ||
| ABC_membrane | 750..1020 | CDD:279056 | 87/269 (32%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1070..1309 | CDD:213216 | 132/236 (56%) | ||
| Abcb11 | NP_113948.1 | PTZ00265 | 150..1314 | CDD:240339 | 491/1177 (42%) |
| Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385 | 651..674 | 6/22 (27%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 196 | 1.000 | Domainoid score | I3030 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1004 | 1.000 | Inparanoid score | I276 |
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44372 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.780 | |||||