| Sequence 1: | NP_523740.3 | Gene: | Mdr50 / 36582 | FlyBaseID: | FBgn0010241 | Length: | 1313 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001335874.1 | Gene: | ABCB1 / 5243 | HGNCID: | 40 | Length: | 1350 | Species: | Homo sapiens |
| Alignment Length: | 1313 | Identity: | 576/1313 - (43%) |
|---|---|---|---|
| Similarity: | 804/1313 - (61%) | Gaps: | 61/1313 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 25 LGAKLEDSDRD----RKSFEP--NKSKKKSKHDESDASDEEDGSQYHEDVKQVSYFQLFRYATKK 83
Fly 84 DRALYVIGLLSAVATGLTTPANSLIFGNLANDMIDLGGL--LESGKSYRA---DDAISTLLLDKV 143
Fly 144 RQFSLQNTYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRMN 208
Fly 209 EDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAK 273
Fly 274 KEVTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFI 338
Fly 339 YASYALAFWYGVGLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAK 403
Fly 404 VFHIIEQIPEINPIDGEGKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPS 468
Fly 469 GCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGRED 533
Fly 534 ATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATS 598
Fly 599 ALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFN 663
Fly 664 LVTTQLGEDDGSVLSPTGDIYKNFDIKDEDEEEIKVLSEDEDE-------------DVMVTDEKN 715
Fly 716 KKKKKKKVKDPNEVKPM--LEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGSILQILSVKD 778
Fly 779 NDQYVRENSNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKA 843
Fly 844 NGTGSLCARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFY 908
Fly 909 MQRTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNTHFR 973
Fly 974 GLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQALIMGTASIANALAFAPNMQKGVS 1038
Fly 1039 AAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKGLELAVSKGQKIAL 1103
Fly 1104 VGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGIVSQEPILFDRTIRENISY 1168
Fly 1169 GDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQLSGGQKQRIAIARALIRNPKIML 1233
Fly 1234 LDEATSALDAESEKVVQDALDAASEGRTTISIAHRLSTVVHSDVIFVFENGLVCEAGDHKQLLAN 1298
Fly 1299 RGLYYTLYKLQSG 1311 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr50 | NP_523740.3 | PTZ00265 | 69..1308 | CDD:240339 | 561/1258 (45%) |
| ABC_membrane | 92..382 | CDD:279056 | 101/294 (34%) | ||
| ABC_MTABC3_MDL1_MDL2 | 431..668 | CDD:213216 | 152/236 (64%) | ||
| ABC_membrane | 750..1020 | CDD:279056 | 105/269 (39%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1070..1309 | CDD:213216 | 146/238 (61%) | ||
| ABCB1 | NP_001335874.1 | PTZ00265 | 123..1337 | CDD:240339 | 552/1231 (45%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 209 | 1.000 | Domainoid score | I2842 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H55496 | |
| Inparanoid | 1 | 1.050 | 1026 | 1.000 | Inparanoid score | I275 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1571 |
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40248 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.760 | |||||