| Sequence 1: | NP_523740.3 | Gene: | Mdr50 / 36582 | FlyBaseID: | FBgn0010241 | Length: | 1313 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032856.2 | Gene: | Abcb4 / 18670 | MGIID: | 97569 | Length: | 1276 | Species: | Mus musculus |
| Alignment Length: | 1300 | Identity: | 563/1300 - (43%) |
|---|---|---|---|
| Similarity: | 801/1300 - (61%) | Gaps: | 65/1300 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 42 NKSKKKSKHDESDASDEEDGSQYHEDVKQVSYFQLFRYATKKDRALYVIGLLSAVATGLTTPANS 106
Fly 107 LIFGNLANDMIDLGG-----------LLESGKSYRADDAISTLLLDKVRQFSLQNTYIGIIMLVC 160
Fly 161 SYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMF 225
Fly 226 VHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGAL 290
Fly 291 SGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYASYALAFWYGVGLVIK 355
Fly 356 GYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEINPIDGE 420
Fly 421 GKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDP 485
Fly 486 QAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGREDATREEIEAAAAAANAAI 550
Fly 551 FIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATSALDTASEAKVQAALEKV 615
Fly 616 SAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFNLVTTQLGEDDGS-VLSP 679
Fly 680 TGDIYKNFDIKDEDEEEIKVLSEDEDEDVMVTDEKN---KKKKKKKVKDPNE------------- 728
Fly 729 VKPM--LEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGSILQILSVKDNDQYVRENSNQYS 791
Fly 792 LYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLCARLSGD 856
Fly 857 AAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQRTLMAKENMGS 921
Fly 922 AKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNTHFRGLVYGLARSLMFF 986
Fly 987 AYAACMYYGTWCVIHRGILFGDVFKVSQALIMGTASIANALAFAPNMQKGVSAAKTIFTFLRRQP 1051
Fly 1052 SIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKGLELAVSKGQKIALVGPSGCGKSTCIQ 1116
Fly 1117 LIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGIVSQEPILFDRTIRENISYGDNARNVTDQEII 1181
Fly 1182 SACKKSNIHEFIANLPLGYDTRMGEKGAQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESE 1246
Fly 1247 KVVQDALDAASEGRTTISIAHRLSTVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQSG 1311 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr50 | NP_523740.3 | PTZ00265 | 69..1308 | CDD:240339 | 556/1268 (44%) |
| ABC_membrane | 92..382 | CDD:279056 | 100/300 (33%) | ||
| ABC_MTABC3_MDL1_MDL2 | 431..668 | CDD:213216 | 145/236 (61%) | ||
| ABC_membrane | 750..1020 | CDD:279056 | 99/269 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1070..1309 | CDD:213216 | 147/238 (62%) | ||
| Abcb4 | NP_032856.2 | PTZ00265 | 30..1269 | CDD:240339 | 557/1273 (44%) |
| ABC_membrane | 58..342 | CDD:279056 | 100/300 (33%) | ||
| ABC_MTABC3_MDL1_MDL2 | 392..628 | CDD:213216 | 145/235 (62%) | ||
| Interaction with HAX1. /evidence=ECO:0000250 | 622..646 | 10/40 (25%) | |||
| ABC_membrane | 712..982 | CDD:279056 | 100/270 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1031..1270 | CDD:213216 | 147/238 (62%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 206 | 1.000 | Domainoid score | I2901 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1050 | 1.000 | Inparanoid score | I261 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42316 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.810 | |||||