DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mdr50 and LOC101883977

DIOPT Version :9

Sequence 1:	NP_523740.3	Gene:	Mdr50 / 36582	FlyBaseID:	FBgn0010241	Length:	1313	Species:	Drosophila melanogaster
Sequence 2:	XP_005174513.2	Gene:	LOC101883977 / 101883977	-ID:	-	Length:	257	Species:	Danio rerio

Alignment Length:	244	Identity:	77/244 - (31%)
Similarity:	132/244 - (54%)	Gaps:	21/244 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LYVIGLLSAVATGLTTPANSLIFGNLANDM----IDLGGLLESGKS--------------YRADD 133
            :.|:|...::..|..||...|::|.:.|..    :::..|.:..|:              .|.|:
Zfish     1 MMVVGSFCSLVHGAATPLMLLVYGMMTNTFVEYEVEILELTDPNKTCINNTISWMNGSAVQRPDN 65

  Fly   134 AISTLLLD---KVRQFSLQNTYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWY 195
            ......:|   ::..|:|....||:.:|:.|:..||.:..||..||..||..:||.|:..::.|:
Zfish    66 TTIYCGVDIEAEMTNFALYYIGIGVGVLILSFFQITFWVSAAARQIQRIRKTYFRKIMRMEIGWF 130

  Fly   196 DFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIA 260
            |.|..||:.:||::|::|:.:.:|::|.:|:..:..|:...::.|:.||:|:||.:...||..:|
Zfish   131 DCNSVGELNTRMSDDINKINNAIADQVSIFIERISTFIFGFMVGFIGGWKLTLVVIAVSPLLGLA 195

  Fly   261 MGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAY 309
            .||:|:|.:||..:|:..||.|..||:..||.||||.||.||.||...|
Zfish   196 AGLMAMAVARLTGRELKAYAKAGAVADEVLSSIRTVAAFGGEHKEAERY 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	77/244 (32%)
		ABC_membrane	92..382	CDD:279056	75/239 (31%)
		ABC_MTABC3_MDL1_MDL2	431..668	CDD:213216
		ABC_membrane	750..1020	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1070..1309	CDD:213216
LOC101883977	XP_005174513.2	ABC_membrane	76..>244	CDD:279056	63/167 (38%)
LOC101883977	XP_005174513.2	MdlB	80..>255	CDD:224055	64/165 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186078at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010