Protein Alignment Mdr50 and tap1

DIOPT Version :9

• Sequence 1: NP_523740.3
• Gene: Mdr50 / 36582
• FlyBaseID: FBgn0010241
• Length: 1313
• Species: Drosophila melanogaster
• Sequence 2: XP_002665053.1
• Gene: tap1 / 100333043
• ZFINID: ZDB-GENE-050517-43
• Length: 731
• Species: Danio rerio
• Alignment Length: 541
• Identity: 185/541 - (34%)
• Similarity: 292/541 - (53%)
• Gaps: 55/541 - (10%)

  Fly   151 TYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKME 215
            |.:.|:..||.::....:|........:|:...|:::|.||:.::|...:|::.||:..|.:.|.
Zfish   207 TLMTIMSAVCEFVCDLIYNITMSRIHTSIQGLVFQAVLKQDIAFFDKATTGDIVSRITTDTNTMS 271

  Fly   216 DGLAEKVVMFVHYLVAFV---GSLVLAFVKGWQLSLVCLT--SLPLTFIAMGLVAVATSRLAKKE 275
            :.|:||:.:.:.|.:..:   ||:::...:     |.|.|  .||:.:|...:......:|:.:.
Zfish   272 ESLSEKLSLLMWYFMRVIFLFGSMLMLSTR-----LCCFTLLGLPVIWIIPEIFGRFYQKLSAQV 331

  Fly   276 VTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYA 340
            ....|.|..||....|.::||::|..|..|...|::.:.....||...               .|
Zfish   332 QDSLAKANEVATETFSSMKTVRSFANEDGETERYRKCLEDTFALNKVE---------------AA 381

  Fly   341 SYALAFW---------------YGVGLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPY 390
            :||::.|               || |.::.|      .:..:|.:::.....:..:..:.:...|
Zfish   382 AYAVSTWTNSMSSLALKVSILYYG-GRLVTG------SDVSSGDLVSFVLYELQFTSAVEVLMSY 439

  Fly   391 IEAFGIAKGACAKVFHIIEQIPEINPIDGEGKKLNEPLTT---IEFKEVEFQYPTRPEVSILNKL 452
            ......|.||..|:|..:::.|::.| ||.    ..|.|.   ::|:.|.|.||.||:..:|..:
Zfish   440 WPHVKKAVGASEKIFEYVDRKPDVPP-DGS----LAPKTLKGHVQFRNVTFAYPKRPDTDVLKNV 499

  Fly   453 NLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPI 517
            :|::..|:..|||||||.||:|.:.|::|||.||.|.:|.:...|......:|..:|.||.|||:
Zfish   500 SLELKAGKITALVGPSGSGKTTVVSLLERFYQPQNGEILLDQKPLLSYKDQYLHEKISVVSQEPV 564

  Fly   518 LFATSIYENIRYGREDATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIAR 582
            |||.|:.|||:||:|:||.|||.|||..|||..||..|||||||..||:|.|:||||||||||||
Zfish   565 LFARSVRENIKYGKENATNEEIYAAARLANAHDFISSLPKGYDTDAGEKGGQVSGGQKQRIAIAR 629

  Fly   583 ALIRDPEILLLDEATSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVE 647
            |||:.|:||:||:|||:|||.||.:|.:||:|.....|.::::||||.|..||.|:.:.:||:||
Zfish   630 ALIQKPQILVLDDATSSLDTESEHRVYSALKKELQSCTVLLISHRLSGVENADHILFLREGELVE 694

  Fly   648 SGTHQELMELKDHYFNLVTTQ 668
            .|.||:|::.:..|...|..|
Zfish   695 EGNHQQLLDKQGFYAEFVKQQ 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	185/541 (34%)
		ABC_membrane	92..382	CDD:279056	51/250 (20%)
		ABC_MTABC3_MDL1_MDL2	431..668	CDD:213216	121/236 (51%)
		ABC_membrane	750..1020	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1070..1309	CDD:213216
tap1	XP_002665053.1	3a01208	42..712	CDD:273363	183/536 (34%)
		ABC_membrane	166..433	CDD:279056	51/252 (20%)
		P-loop_NTPase	467..692	CDD:304359	115/228 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010