Protein Alignment SmydA-1 and smyd4

DIOPT Version :10

• Sequence 1: NP_610944.1
• Gene: SmydA-1 / 36581
• FlyBaseID: FBgn0033917
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: XP_012812690.1
• Gene: smyd4 / 779741
• XenbaseID: XB-GENE-945037
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 126/612 - (20%)
• Similarity: 208/612 - (33%)
• Gaps: 185/612 - (30%)

  Fly     7 CEEPTKNKCSNCNQVSYCSVQHQKQDWKVH--KPSCHPFKIAHNEQLGRHLVATRTIKPYEIVLK 69
            |.|..|.|..  .|.|...::....|...|  ..|| ...:..:.:.||||:|::.|:..|:::.
 Frog   206 CVETVKPKKE--PQTSTERLKEMALDRNPHITNASC-ALHLNFDTRKGRHLLASQNIEQGEVLIW 267

  Fly    70 EAPL--------------VRGPAQISA--PVCLGCLNGIEAEDHIECEQCGWP-LCGPECKSLDE 117
            |...              ::...:|:|  ..|..|||.:.|.  :.|:.|.:. .|..||  :|:
 Frog   268 EEAFASVIIPERKQWRKEIKWDTRITACDHYCHYCLNRVIAS--LPCQYCSFARYCSQEC--MDK 328

  Fly   118 -----HKAECGL-----------------------------------------TKDRGQK----- 131
                 |..||.:                                         ||....|
 Frog   329 AWRSYHYIECSMGDLLLALGMFCHTALRAVLVAGCRLFSQSLEQTGSADATDKTKVCNSKNTYHE 393

  Fly   132 ---------VNVQEFGGPHP-------------LY--TCLSTVRCLLIGETSTEKASKFQDLESL 172
                     ||:......||             ||  .||...:.|:...:.|||        ||
 Frog   394 KYCSSYQSVVNLLPHTENHPAERKFLCGLTAAALYKKLCLIMAKDLVSSTSQTEK--------SL 450

  Fly   173 ESTRRGSNQWKADLVSIGQFI-PKFFK--TQKFTEEEIMKAVGALQINGHE----VPTTDPS--- 227
            .........|.    |:.||: |...:  .|.:...:   ||.|||.|..|    :..::.|
 Frog   451 TKESGTIEDWS----SVRQFLGPTVLRHMLQLYCNAQ---AVTALQENEDESSLSLVKSNKSIRL 508

  Fly   228 HVAVFYTASFTENSCLPNLAKSFNKNGHCI-LWAPREIKKNAHLSICYS--DAMWGTADRQRHLM 289
            ..|||...|...:||.||...||  .|..: :.|.|.|:::..::.||.  ......|:||:.|.
 Frog   509 ATAVFPVLSLLNHSCDPNTTVSF--TGRFVTVRANRPIRRDEEVTHCYGPHKLRMDVAERQQLLK 571

  Fly   290 QTKLFKCACERCVDVTELDTNYSAIKCEDRQCGGLMLPTKADEWNG-------SWRCRECHKQVQ 347
            ....|.|.|:.|.:           :.:.::..|...|....:..|       ..||.....|.|
 Frog   572 DQYFFVCQCKACTE-----------ELKGKKTHGFFCPLCKAQLEGEEALYCTGARCTYTASQTQ 625

  Fly   348 KHYVERILERAGKDIQ-SMEKIAENG--------LKYLKHYEKWLPPQHFHMSEIKILLVQLLAK 403
               :...|.:.|..|| :..::.:|.        :..|...|.:|...|..:.||...|.|..|.
 Frog   626 ---LTSRLNQLGNHIQIAKVQLQDNKTDNAKMTLMSCLSEAECFLSQDHLLLGEIMDHLAQAEAS 687

  Fly   404 D----------QKELMVIPDDRLLLKLNFARELVEL-YEKLTPCEVRTLGTLCFELHSAIAE--Q 455
            |          :|.:.::       |:::....:|| :|.....::...|   ||:..|:..  :
 Frog   688 DGNWKAAAGHLRKSISIV-------KVHYGSSSMELGHELFKLAQILFNG---FEVPDAMRTIME 742

  Fly   456 TRRVALETSLSPKDRLEESLFYVDKCV 482
            .::| |.....|...|.:.|..:::|:
 Frog   743 AQKV-LSMHYGPDHNLVQELKTMEECL 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:460312	8/34 (24%)
		SET_SMYD	<217..301	CDD:380997	26/93 (28%)
smyd4	XP_012812690.1	TPR repeat	106..134	CDD:276809
		TPR repeat	143..173	CDD:276809
		SET_SMYD4	234..583	CDD:380934	80/370 (22%)
		zf-MYND	299..338	CDD:460312	12/42 (29%)